Department of Medicine, Drammen Hospital, Drammen, Norway.
Department of Behavioral Sciences in Medicine and Faculty of Medicine, University of Oslo, Oslo, Norway.
Scand Cardiovasc J. 2021 Apr;55(2):73-81. doi: 10.1080/14017431.2020.1852308. Epub 2020 Dec 4.
To determine longitudinal changes in lifestyle behaviour and lipid management in a chronic coronary heart disease (CHD) population. A multi-centre cohort study consecutively included 1127 patients at baseline in 2014-2015, on average 16 months after a CHD event. Data were collected from hospital records, a questionnaire and clinical examination. Seven hundred and seven of 1021 eligible patients participated in a questionnaire-based follow-up in 2019. Data were analysed with univariate statistics. After a mean follow-up of 4.7 years (SD 0.4) from baseline, the percentage of current smokers (15% versus 16%), obesity (23% versus 25%) and clinically significant symptoms of anxiety (21% versus 17%) and depression (13% versus 14%) remained unchanged, whereas the proportion with low physical activity increased from 53% to 58% ( < .001). The proportions with reduced physical activity level were similar in patients over and under 70 years of age. Most patients were still taking statins (94% versus 92%) and more patients used high-intensity statin (49% versus 54%, < .001) and ezetimibe (5% versus 15%, < .001) at follow-up. 73% reported ≥1 primary-care consultation(s) for CHD during the last year while 27% reported no such follow-up. There were more smokers among participants not attending primary-care consultations compared to those attending (19% versus 14%, = .026). No differences were found for other risk factors. We found persistent suboptimal risk factor control in coronary outpatients during long-term follow-up. Closer follow-up and intensified risk management including lifestyle and psychological health are needed to improved secondary prevention and outcome of CHD. Registered at ClinicalTrials.gov: NCT02309255.Registered at 5 December 2014, registered retrospectively.
为了确定在慢性冠心病(CHD)人群中生活方式行为和血脂管理的纵向变化。一项多中心队列研究连续纳入了 2014-2015 年基线时的 1127 例患者,平均在 CHD 事件后 16 个月。数据来自医院记录、问卷和临床检查。1021 例符合条件的患者中有 707 例参加了 2019 年的基于问卷的随访。采用单变量统计分析数据。从基线开始平均随访 4.7 年(SD 0.4 年)后,当前吸烟者的比例(15%对 16%)、肥胖(23%对 25%)、临床显著焦虑症状(21%对 17%)和抑郁(13%对 14%)保持不变,而体力活动水平较低的比例从 53%增加到 58%( < .001)。70 岁以上和以下的患者减少体力活动的比例相似。大多数患者仍在服用他汀类药物(94%对 92%),更多患者在随访时使用高强度他汀类药物(49%对 54%, < .001)和依折麦布(5%对 15%, < .001)。73%的患者报告在过去一年中至少有 1 次因 CHD 就诊初级保健,而 27%的患者未进行此类随访。与参加者相比,未参加初级保健咨询的参与者中吸烟者比例更高(19%对 14%, = .026)。其他危险因素没有差异。我们发现,在长期随访中,冠心病门诊患者的危险因素控制仍然不理想。需要更密切的随访和强化风险管理,包括生活方式和心理健康,以改善 CHD 的二级预防和结局。在 ClinicalTrials.gov 注册:NCT02309255。于 2014 年 12 月 5 日注册,回顾性注册。