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[胃上皮样平滑肌瘤(平滑肌瘤母细胞瘤)。1例病例分析及文献复习]

[Gastric epithelioid leiomyoma (leiomyoblastoma). Analysis of a case and review of the literature].

作者信息

Waisberg J, Bromberg S H, Gonçalves J E, Guidugli Neto J, Goffi F S

机构信息

Serviço de Gastroenterologia Cirúrgica, Hospital do Servidor Público Estadual Francisco Mortao de Oliveira.

出版信息

Arq Gastroenterol. 1986 Oct-Dec;23(4):236-41.

PMID:3327489
Abstract

The authors report a case of gastric epithelial leiomyoma (leiomyoblastoma). Macroscopically, such tumors resemble leiomyoma, with a biological behavior between leiomyoma and leiomyosarcoma. A review of the medical literature indicates that gastrointestinal bleeding is the most usual manifestation. Gastrointestinal seriography and endoscopy are the most utilized diagnostic exams. The endoscopic biopsy, many times, is unable to confirm the malignant or benign nature of the tumor. It is emphasized the importance of identifying the potentially malignant tendency of the tumor, indicated, mainly, by histology and mitotic counting. The treatment is surgical and consists of local or gastric resection, according to the neoplastic localization, its extension, infiltration, biological nature and the presence of multiple tumors. In the case reported, the patient was operated in urgency because of hemoperitoneum and the source of bleeding was a neoplastic vessel in the anterior wall of the antrum, which was not resected at that time. Later on, a biopsy of the gastric tumor performed during a routine surgery disclosed the real nature of the disease. Once the histopathological diagnostic was made and its potential malignant evolution detected the patient was re-operated. A partial gastrectomy with removal of the antrum was performed. Now, the patient has been asymptomatic with no evidences of metastasis after 30 months of the diagnostic.

摘要

作者报告了一例胃上皮平滑肌瘤(平滑肌瘤样细胞瘤)。从宏观上看,此类肿瘤类似于平滑肌瘤,其生物学行为介于平滑肌瘤与平滑肌肉瘤之间。医学文献回顾表明,胃肠道出血是最常见的表现。胃肠道造影和内镜检查是最常用的诊断方法。内镜活检很多时候无法确定肿瘤的恶性或良性性质。强调了识别肿瘤潜在恶性倾向的重要性,这主要通过组织学和有丝分裂计数来表明。治疗方法为手术,根据肿瘤的定位、范围、浸润情况、生物学性质以及是否存在多个肿瘤,可进行局部切除或胃切除。在所报告的病例中,患者因腹腔积血而紧急手术,出血源是胃窦前壁的一个肿瘤血管,当时未予切除。后来,在常规手术中对胃肿瘤进行活检,揭示了疾病的真实性质。一旦做出组织病理学诊断并检测到其潜在的恶性进展,患者再次接受手术。进行了胃窦切除的部分胃切除术。现在,患者在确诊30个月后无症状,无转移迹象。

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