Department of Rheumatology, Division of Medicine, District General Hospital of Førde, Førde, Norway.
Department of Radiology, District General Hospital of Førde, PO Box 1000, 6807, Førde, Norway.
BMC Musculoskelet Disord. 2020 Dec 4;21(1):811. doi: 10.1186/s12891-020-03842-w.
It is mechanically plausible that osteoporosis leads to more severe peripheral fractures, but studies investigating associations between BMD and radiographically verified complexity of distal radius fractures are scarce. This study aims to study the association between osteoporosis, as well as other risk factors for fracture, and the AO classification of distal radius fractures.
In this observational study, 289 consecutive patients aged ≥40 years with a distal radius fracture were included. Bone mineral density (BMD) of the hips and spine was measured by dual-energy x-ray absorptiometry (DXA), and comorbidities, medication, physical activity, smoking habits, body mass index (BMI), and history of previous fracture were registered. The distal radius fractures were classified according to the Müller AO system (AO) (type B and C regarded as most complex).
Patients with osteoporosis (n = 130) did not have increased odds of a more complex distal radius fracture (type B + C, n = 192)) (n = vs type A (n = 92) (OR 1.1 [95% CI 0.5 to 2.3]) compared to those with osteopenia /normal BMD (n = 159). Patients with AO fracture types A or C had a higher prevalence of osteoporosis than patients with type B fracture.
Distal radius fracture patients with osteoporosis did not sustain more complex fractures than those with osteopenia/normal BMD according to the AO classification system. The AO classification of distal radius fracture cannot be used to decide which patients should be referred to DXA scan and considered for secondary fracture prevention.
从力学角度来看,骨质疏松症可能导致更严重的外周骨折,但研究骨折风险因素与桡骨远端骨折复杂性之间关系的相关文献较少。本研究旨在研究骨质疏松症以及其他骨折风险因素与桡骨远端骨折的 AO 分类之间的关系。
在这项观察性研究中,共纳入 289 例年龄≥40 岁的桡骨远端骨折连续患者。通过双能 X 线吸收法(DXA)测量髋部和脊柱的骨密度(BMD),并记录合并症、药物使用、身体活动、吸烟习惯、体重指数(BMI)和既往骨折史。桡骨远端骨折按 Müller AO 系统(AO)分类(B 型和 C 型视为最复杂)。
骨质疏松症患者(n=130)发生更复杂的桡骨远端骨折(B+C 型,n=192)的可能性并不高于骨量减少/正常 BMD 患者(n=159)(n= vs A 型(n=92)(OR 1.1[95%CI 0.5 至 2.3])。与 B 型骨折患者相比,A 或 C 型 AO 骨折患者骨质疏松症的患病率更高。
根据 AO 分类系统,骨质疏松症桡骨远端骨折患者的骨折复杂性并不高于骨量减少/正常 BMD 患者。桡骨远端骨折的 AO 分类不能用于决定哪些患者应转至 DXA 扫描并考虑进行二级骨折预防。