Department Ophthalmology and Vision Sciences, Toronto, Ontario, Canada; Faculty of Medicine, University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada.
Faculty of Medicine, University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada.
J Emerg Med. 2021 Feb;60(2):192-196. doi: 10.1016/j.jemermed.2020.10.013. Epub 2020 Dec 1.
Patients who experienced transient monocular vision loss (TMVL) commonly present to the emergency department for evaluation. Although multiple etiologies can cause TMVL, it is most important to identify patients with retinal ischemia and those with vasculitis (giant cell arteritis) as the cause of TMVL. Patients with transient retinal ischemia have the same risk of cardiovascular events and death as patients who experienced transient brain ischemia. Patients with giant cell arteritis are at imminent risk of visual loss.
A 65-year-old man noticed three separate episodes of sudden onset of blurry vision in one eye. Ophthalmologic examination was normal but, as his symptoms were compatible with transient retinal ischemic attack, urgent investigations were initiated. He had normal inflammatory markers but computed tomography angiogram of the brain and neck demonstrated a large plaque in the ipsilateral internal carotid artery. Double anti-platelet therapy was started and stenting of the involved carotid artery was performed. The patient was symptom-free at the last follow-up. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Patients with retinal ischemia as the etiology of TMVL are at high risk of cardiovascular events and death. Their risk of cerebrovascular accidents is highest within 48 h from the episode of TMVL, thus they should have an urgent ophthalmologic examination and, if it is unrevealing, inflammatory markers should be checked and an urgent stroke prevention protocol should be initiated. Appropriate management with medical or surgical interventions significantly reduces morbidity and mortality in these patients.
经历一过性单眼视力丧失(TMVL)的患者通常会到急诊科就诊进行评估。虽然多种病因可导致 TMVL,但识别视网膜缺血和血管炎(巨细胞动脉炎)引起的 TMVL 患者至关重要。一过性视网膜缺血患者发生心血管事件和死亡的风险与经历一过性脑缺血的患者相同。巨细胞动脉炎患者有即将发生视力丧失的风险。
一名 65 岁男性注意到一只眼突然出现三次单眼视力模糊。眼科检查正常,但由于他的症状符合一过性视网膜缺血发作,因此紧急进行了检查。他的炎症标志物正常,但脑和颈部 CT 血管造影显示同侧颈内动脉有一个大斑块。开始使用双联抗血小板治疗,并对受累颈动脉进行支架置入术。患者最后一次随访时无症状。
为什么急诊医生需要了解这个情况?:以视网膜缺血为病因的 TMVL 患者发生心血管事件和死亡的风险很高。他们在 TMVL 发作后 48 小时内发生脑血管意外的风险最高,因此应紧急进行眼科检查,如果结果正常,应检查炎症标志物并启动紧急卒中预防方案。这些患者进行适当的医疗或手术干预可显著降低发病率和死亡率。