State Key Laboratory for Hubei New Textile Materials and Advanced Processing Technologies, School of Textile Science and Engineering, Wuhan Textile University, Wuhan, 430200, China.
State Key Laboratory for Hubei New Textile Materials and Advanced Processing Technologies, School of Textile Science and Engineering, Wuhan Textile University, Wuhan, 430200, China.
Carbohydr Polym. 2021 Feb 1;253:117214. doi: 10.1016/j.carbpol.2020.117214. Epub 2020 Oct 13.
Nanofibrils derived from natural biopolymers have received extensive interest due to their exceptional mechanical properties and excellent biocompatibility. To fabricate biocompatible chitosan nanocomposites with high mechanical performance, silkworm silks were deconstructed into nanofibrils as structural and mechanical reinforcement of chitosan. After dispersing silk nanofibrils in chitosan solution, a set of nanocomposites, including film, porous scaffold, filament, and nanofibrous sponge, could be fabricated from the blended solutions. Silk nanofibrils could be uniformly dispersed in chitosan solution, and formed multi-dimensional nanocomposites. The nanocomposites exhibited enhanced mechanical strength and thermal stability, and provided a biomimetic nanofibrous structure for biomaterial applications. The enhancement in mechanical properties can be attributed to the interaction between the nanofibril phase and the chitosan matrix. As the polysaccharide/protein bionanocomposites derived from natural biopolymers, these materials offer new opportunities for biomaterial application by virtue of their biocompatibility and biodegradability, as well as enhanced mechanical properties and controllable mesoscopic structure.
由于具有优异的机械性能和良好的生物相容性，源自天然生物聚合物的纳米纤维受到了广泛关注。为了制备具有高机械性能的生物相容性壳聚糖纳米复合材料，将家蚕丝解构为纳米纤维，作为壳聚糖的结构和力学增强材料。将丝纳米纤维分散在壳聚糖溶液中后，可由混合溶液制备出包括薄膜、多孔支架、纤维和纳米纤维海绵在内的一系列纳米复合材料。丝纳米纤维可均匀分散在壳聚糖溶液中，并形成多维纳米复合材料。纳米复合材料表现出增强的机械强度和热稳定性，并为生物材料应用提供了仿生纳米纤维结构。机械性能的增强归因于纳米纤维相与壳聚糖基质之间的相互作用。作为源自天然生物聚合物的多糖/蛋白质生物纳米复合材料，这些材料由于其生物相容性和可生物降解性以及增强的机械性能和可控制的介观结构，为生物材料的应用提供了新的机会。
