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肝移植术后患儿发生以化脓性肝脓肿为表现的移植肝原发性结核。

Primary tuberculosis of the graft masquerading pyogenic liver abscess in a pediatric liver recipient.

机构信息

Department of Pediatric Gastroenterology & Hepatology, Bharat Institute of Higher Education and Research, Chennai, India.

Department of Histopathology, Bharat Institute of Higher Education and Research, Chennai, India.

出版信息

Transpl Infect Dis. 2021 Jun;23(3):e13533. doi: 10.1111/tid.13533. Epub 2020 Dec 6.

Abstract

Primary tuberculosis (TB) of the graft presenting as multiple liver abscesses is previously unreported. A 14-month-old male child in the early post liver transplant (LT) period presented with high-grade fever spikes and on evaluation was found to have multiple pyogenic liver abscesses (PLA) in the CT abdomen. His fever was not responding to intravenous antibiotics and liver biopsy was done which showed numerous acid fast bacilli. Genetic analysis confirmed the bacilli as Mycobacterium tuberculosis (MTB). Timely diagnosis and prompt introduction of antituberculosis therapy were lifesaving.

摘要

原发性移植肝结核(TB)以多发肝脓肿为表现此前尚未见报道。1 例肝移植术后早期 14 月龄男童,表现为高热,腹部 CT 显示多发化脓性肝脓肿。静脉应用抗生素后体温仍有波动,行肝活检提示大量抗酸杆菌。基因分析证实为结核分枝杆菌(MTB)。及时诊断并尽早开始抗结核治疗可挽救生命。

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