Department of Internal Medicine, Keio University School of Medicine, Japan.
Department of Nuclear Medicine, Saitama Medical University International Medical Center, Japan.
Intern Med. 2021 May 15;60(10):1555-1560. doi: 10.2169/internalmedicine.6381-20. Epub 2020 Dec 7.
A 71-year-old man complained of nausea and loss of appetite for eight months prior to admission. He was transported to a hospital with disorientation and diagnosed with primary hyperparathyroidism by laboratory examinations. However, ultrasonography, computed tomography, and technetium-99m labeled methoxyisobutyl isonitrile (Tc-MIBI) with single-photon emission computed tomography did not yield definite results. In contrast, somatostatin receptor scintigraphy successfully identified the lesion responsible for the over-secretion of parathyroid hormone within the middle mediastinum. The tumor was successfully resected by surgery, and a histopathological analysis confirmed the parathyroid adenoma nature of the tumor.
一位 71 岁男性,因恶心和食欲不振入院前 8 个月。他被送往医院,出现定向障碍,并通过实验室检查诊断为原发性甲状旁腺功能亢进症。然而,超声、计算机断层扫描和锝-99m 标记甲氧异丁基异腈(Tc-MIBI)单光子发射计算机断层扫描未得出明确结果。相比之下,生长抑素受体闪烁显像术成功确定了位于纵隔中部导致甲状旁腺激素过度分泌的病灶。肿瘤通过手术成功切除,组织病理学分析证实肿瘤为甲状旁腺腺瘤。