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透明质酸软组织填充剂继发脓肿管理的病例系列及综述与推荐管理指南

Case Series and Review on Managing Abscesses Secondary to Hyaluronic Acid Soft Tissue Fillers with Recommended Management Guidelines.

作者信息

Diwan Zoya, Trikha Sanjay, Etemad-Shahidi Sepideh, Virmani Surbhi, Denning Catherine, Al-Mukhtar Yusra, Rennie Christopher, Penny Amanda, Jamali Yalda, Edwards Parrish Nina Cassandra

机构信息

Dr. Diwan is President of Academic Aesthetics Mastermind Group and the medical director of Trikwan Aesthetics in London, United Kingdom.

Dr. Trikha is Vice President of Academic Aesthetics Mastermind Group and the director of Trikwan Aesthetics in London, United Kingdom.

出版信息

J Clin Aesthet Dermatol. 2020 Nov;13(11):37-43. Epub 2020 Nov 1.

Abstract

With the number of aesthetic soft tissue filler treatments rapidly increasing, we have witnessed an increase in complications associated with such treatments. While rare, abscesses can arise as a result of these treatments, and current detailed guidelines do not exist detailing exactly how to manage them. Our aim was to develop evidence-based and experience-based guidelines on how to, specifically, manage abscesses secondary to hyaluronic acid dermal fillers. A thorough MEDLINE literature search of keywords, including and , was completed to collect specific cases of abscesses secondary to soft tissue filler. Inclusion criteria involved papers published from 2010 to 2020 that focused specifically on soft tissue fillers in the face. In addition, we looked at papers that discussed abscesses secondary to soft tissue fillers in general and their management. We also reported three cases of abscesses secondary to hyaluronic acid dermal fillers that have been described by three different practitioners, detailing their history, examination, management, and outcomes. Experience and evidence have been collated to produce management guidelines. It is clear that each case is unique, but there is no current universal consensus on the risk assessment before treatment nor general management of abscesses secondary to soft tissue filler. The majority of the reports and cases discussed in the paper suggested the use of co-amoxiclav along with a macrolide or quinolone for at least two weeks. Incision and drainage are universally accepted as gold standard management. Microbiology, sensitivities, and cultures are also recommended. Hyaluronidase use, while controversial, is encouraged in effectively managing abscesses secondary to hyaluronic acid dermal filler.

摘要

随着美容软组织填充剂治疗数量的迅速增加,我们目睹了与此类治疗相关的并发症有所增多。虽然罕见,但这些治疗可能会引发脓肿,而目前尚无详细的指南确切说明如何处理它们。我们的目标是制定基于证据和经验的指南,具体说明如何处理透明质酸真皮填充剂继发的脓肿。通过对MEDLINE数据库进行全面的关键词文献检索,包括……,以收集软组织填充剂继发脓肿的具体病例。纳入标准包括2010年至2020年发表的专门关注面部软组织填充剂的论文。此外,我们还查阅了一般讨论软组织填充剂继发脓肿及其处理的论文。我们还报告了三位不同从业者描述的三例透明质酸真皮填充剂继发脓肿的病例,详细介绍了它们的病史、检查、处理及结果。我们整理了经验和证据以制定处理指南。显然,每个病例都是独特的,但目前在治疗前的风险评估以及软组织填充剂继发脓肿的一般处理方面尚无普遍共识。本文讨论的大多数报告和病例建议使用阿莫西林克拉维酸联合大环内酯类或喹诺酮类药物至少两周。切开引流被普遍认为是金标准处理方法。还建议进行微生物学检查、药敏试验和培养。透明质酸酶的使用虽然存在争议,但在有效处理透明质酸真皮填充剂继发脓肿方面受到鼓励。

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本文引用的文献

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