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全腕关节融合术后再次手术相关的并发症及因素

Complications and Factors Associated with Reoperation following Total Wrist Fusion.

作者信息

Hazewinkel M H J, Lans Jonathan, Lunn Kiera N, Garg Rohit, Eberlin Kyle R, Chen Neal C

机构信息

Department of Orthopaedic Surgery, Hand and Upper Extremity Service, General Hospital, Harvard Medical School, Boston, Massachusetts.

Department of Plastic Surgery, Hand Surgery, and Peripheral Nerve Surgery, General Hospital, Harvard Medical School, Boston, Massachusetts.

出版信息

J Wrist Surg. 2020 Dec;9(6):498-508. doi: 10.1055/s-0040-1714683. Epub 2020 Aug 21.

DOI:10.1055/s-0040-1714683
PMID:33282536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7708030/
Abstract

Total wrist fusion can be elected to relieve pain in patients with osteoarthritis and rheumatoid arthritis. This study aimed to investigate the overall complications and the factors associated with reoperation and soft tissue complication after total wrist fusion.  We retrospectively identified adult patients who underwent total wrist fusion using Current Procedural Terminology (CPT) codes, International Classification of Diseases, Ninth and Tenth Revision (ICD-9 and ICD-10) and verified these by medical chart review. We included patients (  = 215) who were treated at a single institutional system from January 1, 2002 to January 1, 2019. The mean age was 53.3 ± 15.0 years and the median follow-up was 6.1 years (interquartile range [IQR] =1.7-9.0). The most common indications for wrist fusion included inflammatory arthritis (  = 66, 31%), degenerative arthritis (  = 59, 27%), and posttraumatic arthritis (  = 47, 22%). All wrist fusions were performed using a dorsal fusion plate or dorsal spanning plate, either with a local autograft (  = 167, 78%), iliac crest autograft (  = 2, 1.0%), allograft (  = 7, 3.3%), a combination of both (  = 16, 7.4%), or without a graft (  = 23, 11%). We performed a multivariable logistic regression to evaluate factors associated with reoperation. In addition, we performed a similar analysis to identify the factors associated with soft tissue complication after total wrist fusion.  Forty-one (19%) patients underwent reoperation at a median of 6.9 months (IQR = 3.9-18). The indications included symptomatic implants (  = 12, 27%), implant failures (  = 8, 20%), infections (  = 7, 17%), and nonunions (  = 6, 15%). In multivariable analysis, total wrist fusion of the dominant hand (odds ratio [OR]: 2.2, 95% confidence interval [CI]: 1.1-4.7,  = 0.033) was associated with a higher reoperation rate. Soft tissue complications occurred in 20 patients (9.3%) consisting of hematomas (  = 8, 3.7%), observed blistering (  = 5, 2.3%), and observed wound dehiscence (  = 4, 1.9%). In multivariable analysis, smoking (OR: 2.5, CI: 0.95-6.4,  = 0.010) was independently associated with soft tissue complication after total wrist fusion. Seventy-two (33%) patients had a postoperative complication including symptomatic hardware (  = 16, 7.4%), implant failure (  = 11, 5.1%), infection (  = 11, 5.1%), nonunion (  = 8, 3.7%), and carpal tunnel syndrome (  = 4, 1.9%).  Roughly one-third (33%) of the patients undergoing total wrist fusion experience a postoperative complication and 19% of the patients underwent a reoperation. Total wrist fusion of the dominant hand results in higher reoperation rates. The risk of a soft tissue complication after total wrist fusion is increased in smokers.

摘要

全腕关节融合术可用于缓解骨关节炎和类风湿关节炎患者的疼痛。本研究旨在调查全腕关节融合术后的总体并发症以及与再次手术和软组织并发症相关的因素。

我们使用当前操作术语(CPT)编码、国际疾病分类第九版和第十版(ICD - 9和ICD - 10)回顾性地确定了接受全腕关节融合术的成年患者,并通过病历审查进行了验证。我们纳入了2002年1月1日至2019年1月1日在单一机构系统接受治疗的患者(n = 215)。平均年龄为53.3±15.0岁,中位随访时间为6.1年(四分位间距[IQR]=1.7 - 9.0)。腕关节融合最常见的适应证包括炎性关节炎(n = 66,31%)、退行性关节炎(n = 59,27%)和创伤后关节炎(n = 47,22%)。所有腕关节融合术均使用背侧融合钢板或背侧跨越钢板,同时使用局部自体骨移植(n = 167,78%)、髂嵴自体骨移植(n = 2,1.0%)、同种异体骨移植(n = 7,3.3%)、两者联合使用(n = 16,7.4%)或不进行移植(n = 23,11%)。我们进行了多变量逻辑回归分析以评估与再次手术相关的因素。此外,我们进行了类似的分析以确定全腕关节融合术后与软组织并发症相关的因素。

41例(19%)患者在中位时间6.9个月(IQR = 3.9 - 18)时接受了再次手术。适应证包括有症状的植入物(n = 12,27%)、植入物失败(n = 8,20%)、感染(n = 7,17%)和骨不连(n = 6,15%)。在多变量分析中,优势手的全腕关节融合术(优势比[OR]:2.2,95%置信区间[CI]:1.1 - 4.7,P = 0.033)与更高的再次手术率相关。20例患者(9.3%)发生了软组织并发症,包括血肿(n = 8,3.7%)、观察到的水泡形成(n = 5,2.3%)和观察到的伤口裂开(n = 4,1.9%)。在多变量分析中,吸烟(OR:2.5,CI:0.95 - 6.4,P = 0.010)与全腕关节融合术后的软组织并发症独立相关。72例(33%)患者出现了术后并发症,包括有症状的内固定物(n = 16,7.4%)、植入物失败(n = 11,5.1%)、感染(n = 11,5.1%)、骨不连(n = 8,3.7%)和腕管综合征(n = 4,1.9%)。

接受全腕关节融合术的患者中约三分之一(33%)经历了术后并发症,19%的患者接受了再次手术。优势手的全腕关节融合术导致更高的再次手术率。吸烟者全腕关节融合术后发生软组织并发症的风险增加。