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新加坡机器人肝、胰和胆道手术的应用:单机构 100 例连续病例的初步经验。

Adoption of Robotic Liver, Pancreatic and Biliary Surgery in Singapore: A Single Institution Experience with Its First 100 Consecutive Cases.

机构信息

Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital, Singapore.

出版信息

Ann Acad Med Singap. 2020 Oct;49(10):742-748.

Abstract

INTRODUCTION

Presently, robotic hepatopancreatobiliary surgery (RHPBS) is increasingly adopted worldwide. This study reports our experience with the first 100 consecutive cases of RHPBS in Singapore.

METHODS

Retrospective review of a single-institution prospective database of the first 100 consecutive RHPBS performed over 6 years from February 2013 to February 2019. Eighty-six cases were performed by a single surgeon.

RESULTS

The 100 consecutive cases included 24 isolated liver resections, 48 pancreatic surgeries (including 2 bile duct resections) and 28 biliary surgeries (including 8 with concomitant liver resections). They included 10 major hepatectomies, 15 pancreaticoduodenectomies, 6 radical resections for gallbladder carcinoma and 8 hepaticojejunostomies. The median operation time was 383 minutes, with interquartile range (IQR) of 258 minutes and there were 2 open conversions. The median blood loss was 200ml (IQR 350ml) and 15 patients required intra-operative blood transfusion. There were no post-operative 90-day nor in-hospital mortalities but 5 patients experienced major (> grade 3a) morbidities. The median post-operative stay was 6 days (IQR 5 days) and there were 12 post-operative 30-day readmissions. Comparison between the first 50 and the subsequent 50 patients demonstrated a significant reduction in blood loss, significantly lower proportion of malignant indications, and a decreasing frequency in liver resections performed.

CONCLUSION

Our experience with the first 100 consecutive cases of RHPBS confirms its feasibility and safety when performed by experienced laparoscopic hepatopancreatobiliary surgeons. It can be performed for even highly complicated major hepatopancreatobiliary surgery with a low open conversion rate.

摘要

简介

目前,机器人肝胆胰手术(RHPBS)在全球范围内得到了越来越多的应用。本研究报告了我们在新加坡进行的前 100 例连续 RHPBS 经验。

方法

回顾性分析了 2013 年 2 月至 2019 年 2 月期间,由一位外科医生连续完成的前 100 例连续 RHPBS 的单中心前瞻性数据库。

结果

这 100 例连续病例包括 24 例单独的肝切除术、48 例胰腺手术(包括 2 例胆管切除术)和 28 例胆道手术(包括 8 例伴肝切除术)。其中包括 10 例大肝切除术、15 例胰十二指肠切除术、6 例胆囊癌根治性切除术和 8 例胆肠吻合术。中位手术时间为 383 分钟,四分位距(IQR)为 258 分钟,有 2 例中转开腹。中位出血量为 200ml(IQR 350ml),15 例患者需要术中输血。无术后 90 天和住院期间死亡,但有 5 例发生严重(>3a 级)并发症。中位术后住院时间为 6 天(IQR 5 天),有 12 例术后 30 天再入院。前 50 例和后 50 例患者的比较显示,出血量明显减少,恶性指征比例显著降低,肝切除术的频率也有所降低。

结论

我们在进行的前 100 例连续 RHPBS 经验证实了其在有经验的腹腔镜肝胆胰外科医生手中的可行性和安全性。即使是高度复杂的主要肝胆胰手术,其中转开腹率也很低。

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