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Suspected Pulmonary Embolism Postcesarean Section in a Patient with Autosomal Dominant Polycystic Kidney Disease.一名常染色体显性多囊肾病患者剖宫产术后疑似肺栓塞
Niger Med J. 2020 Jul-Aug;61(4):223-225. doi: 10.4103/nmj.NMJ_99_20. Epub 2020 Aug 4.
2
Rupture of a previously documented small asymptomatic intracranial aneurysm in a patient with autosomal dominant polycystic kidney disease. Case report.一名常染色体显性遗传性多囊肾病患者,此前记录的无症状性小颅内动脉瘤破裂。病例报告。
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Intracranial aneurysms in patients receiving kidney transplantation for autosomal dominant polycystic kidney disease.常染色体显性多囊肾病患者接受肾移植术后的颅内动脉瘤。
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Autosomal dominant polycystic kidney disease in pregnancy complicated by twin gestation and severe preeclampsia: a case report.妊娠合并双胎妊娠和重度子痫前期的常染色体显性多囊肾病:一例报告
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A 4-year-old girl with autosomal dominant polycystic kidney disease complicated by a ruptured intracranial aneurysm.一名4岁女童,患常染色体显性多囊肾病,并发颅内动脉瘤破裂。
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An autopsy case of subarachnoid hemorrhage due to ruptured cerebral aneurysm associated with polycystic kidney disease caused by a novel PKD1 mutation.一例因新型PKD1突变导致的多囊肾病相关脑动脉瘤破裂引起蛛网膜下腔出血的尸检病例。
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Intracranial aneurysms in patients with autosomal dominant polycystic kidney disease: prevalence, risk of rupture, and management. A systematic review.常染色体显性多囊肾病患者的颅内动脉瘤:患病率、破裂风险及管理。一项系统评价。
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Cerebral Aneurysms in Autosomal Dominant Polycystic Kidney Disease: A Comparison of Management Approaches.常染色体显性多囊肾病相关的颅内动脉瘤:管理方法的比较。
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A case of congenital left ventricular diverticulum in a patient with autosomal dominant polycystic kidney disease: possible mechanistic link between polycystin and ventricular diverticulum.一名常染色体显性遗传性多囊肾病患者合并先天性左心室憩室:多囊蛋白与心室憩室之间可能的机制联系。
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Empowering women at the heart of autosomal dominant polycystic kidney disease: Addressing unique challenges gender-sensitive approach.以常染色体显性多囊肾病为核心赋予女性力量:采用对性别敏感的方法应对独特挑战。
Womens Health (Lond). 2025 Jan-Dec;21:17455057251345944. doi: 10.1177/17455057251345944. Epub 2025 Jul 19.

本文引用的文献

1
Clinical presentation and outcome of autosomal dominant polycystic kidney disease in Nigeria.尼日利亚常染色体显性多囊肾病的临床表现及转归
Afr Health Sci. 2018 Sep;18(3):671-680. doi: 10.4314/ahs.v18i3.25.
2
Sonographic analysis of adult polycystic kidney disease: retrospective data from South-East Nigeria.
Niger J Clin Pract. 2015 Mar-Apr;18(2):178-82. doi: 10.4103/1119-3077.151037.
3
Successful pregnancy in a patient with autosomal dominant polycystic kidney disease on long-term hemodialysis.长期血液透析的常染色体显性遗传性多囊肾病患者成功妊娠。
J Korean Med Sci. 2014 Feb;29(2):301-4. doi: 10.3346/jkms.2014.29.2.301. Epub 2014 Jan 28.
4
Pregnancy in chronic kidney disease.慢性肾脏病患者的妊娠问题。
Adv Chronic Kidney Dis. 2013 May;20(3):223-8. doi: 10.1053/j.ackd.2013.02.001.
5
Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).常染色体显性多囊肾病(ADPKD)的纤维化与进展
Biochim Biophys Acta. 2011 Oct;1812(10):1327-36. doi: 10.1016/j.bbadis.2011.06.012. Epub 2011 Jul 1.
6
Autosomal dominant polycystic kidney disease: emerging concepts of pathogenesis and new treatments.
Cleve Clin J Med. 2009 Feb;76(2):97-104. doi: 10.3949/ccjm.76a.gr001.
7
Management of cerebral aneurysms in autosomal dominant polycystic kidney disease.常染色体显性多囊肾病中脑动脉瘤的管理
J Am Soc Nephrol. 2002 Jan;13(1):269-276. doi: 10.1681/ASN.V131269.
8
Autosomal dominant polycystic kidney disease: symptoms and clinical findings.常染色体显性多囊肾病:症状与临床发现
Q J Med. 1984 Autumn;53(212):511-22.

一名常染色体显性多囊肾病患者剖宫产术后疑似肺栓塞

Suspected Pulmonary Embolism Postcesarean Section in a Patient with Autosomal Dominant Polycystic Kidney Disease.

作者信息

Badejoko Olusegun O, Dada Olufunke F, Ubom Akaninyene E, Ajayeoba Olumuyiwa T

机构信息

Department of Obstetrics, Gynaecology and Perinatology, Obafemi Awolowo University, Ile-Ife, Nigeria.

Department of Obstetrics and Gynaecology, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

出版信息

Niger Med J. 2020 Jul-Aug;61(4):223-225. doi: 10.4103/nmj.NMJ_99_20. Epub 2020 Aug 4.

DOI:10.4103/nmj.NMJ_99_20
PMID:33284866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7688026/
Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetically inherited kidney disease worldwide. It is however relatively underdiagnosed in Africans because its diagnosis is often incidental. During pregnancy, ADPKD is associated with increased risk of preeclampsia and venous thromboembolism. The case of a 33-year-old lady incidentally diagnosed with ADPKD during pregnancy is presented. She developed preeclampsia at term and had cesarean delivery of twins. She however suffered cardiopulmonary arrest postoperatively and this created a treatment dilemma because therapeutic anticoagulation which was the primary treatment for her suspected pulmonary embolism was absolutely contraindicated if the actual cause of her collapse was ruptured cerebral aneurysm which was also a feature of ADPKD. We decided to resuscitate aggressively and perform an urgent cranial computed tomography which ruled out intracranial hemorrhage. We then commenced anticoagulation and she made an excellent recovery. This case illustrates the importance of a timely multidisciplinary approach to patient management.

摘要

常染色体显性多囊肾病(ADPKD)是全球最常见的遗传性肾病。然而,在非洲人中它相对诊断不足,因为其诊断往往是偶然的。在怀孕期间,ADPKD与子痫前期和静脉血栓栓塞风险增加有关。本文介绍了一位33岁女性在怀孕期间偶然诊断出ADPKD的病例。她足月时发生子痫前期并剖宫产下双胞胎。然而,她术后发生心肺骤停,这造成了治疗困境,因为如果她虚脱的实际原因是脑动脉瘤破裂(这也是ADPKD的一个特征),那么作为疑似肺栓塞主要治疗方法的治疗性抗凝是绝对禁忌的。我们决定积极进行复苏并紧急进行头颅计算机断层扫描,排除了颅内出血。然后我们开始抗凝治疗,她恢复得很好。这个病例说明了及时采取多学科方法进行患者管理的重要性。