北撒丁岛人群中钙代谢与良性阵发性位置性眩晕的关系。

Relationship between calcium metabolism and benign paroxysmal positional vertigo in north Sardinia population.

机构信息

Azienda Ospedaliero Universitaria, Otolaryngology Division, Sassari, Italy.

Otolaryngology, Mater Olbia Hospital, Olbia, Italy.

出版信息

J Vestib Res. 2020;30(6):375-382. doi: 10.3233/VES-200025.

DOI:10.3233/VES-200025

PMID:33285658

Abstract

BACKGROUND

Benign paroxysmal positional vertigo (BPPV) has a reported recurrence ranging from 26.8 to 50%. Osteoporosis and Vitamin D deficiency seems to have an impact on recurrence of BPPV.

OBJECTIVE

to evaluate the impact of osteoporosis and Vitamin D deficiency on recurrence of BPPV.

METHODS

73 consecutive patients were divided in two groups according to the presence (group 1) or absence (group 0) of a recurrent episode. BMD, femoral and lumbar T-scores and Vitamin D levels were recorded. Statistical analysis was performed to investigate correlations.

RESULTS

patients in group 1 had statistically significant lower values of both femoral (-1,62±1,06 vs. -0,53±1,51; p = 0,001), lumbar T-score (-2,10±1,19 vs -0, 53±1.51, p = 0.001) and Vitamin D (19.53±15.33). The values of femoral T-score and Vitamin D could be combined in a model able to properly classify 65.8% of the cases (p = 0.002) as isolated or recurrent BPPV, with high accuracy (AUC 0.710 [0.590 -0.830]).

CONCLUSION

present data show a probable correlation between osteoporosis and Vitamin D with recurrent BPPV.

摘要

背景

良性阵发性位置性眩晕（BPPV）的复发率报告范围为 26.8%至 50%。骨质疏松症和维生素 D 缺乏似乎对 BPPV 的复发有影响。

目的

评估骨质疏松症和维生素 D 缺乏对 BPPV 复发的影响。

方法

73 例连续患者根据是否存在（第 1 组）或不存在（第 0 组）复发性发作分为两组。记录骨密度、股骨和腰椎 T 评分和维生素 D 水平。进行统计分析以调查相关性。

结果

第 1 组患者的股骨（-1.62±1.06 对-0.53±1.51；p=0.001）、腰椎 T 评分（-2.10±1.19 对-0.53±1.51，p=0.001）和维生素 D（19.53±15.33）值均有统计学显著降低。股骨 T 评分和维生素 D 值可以组合成一个模型，能够正确分类 65.8%的病例（p=0.002）为孤立性或复发性 BPPV，准确性高（AUC 0.710 [0.590-0.830]）。