Ran Qiang, Yu Yang, Li Tong, Fan Xiaohong
Chengdu University of Traditional Chinese Medicine.
Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China.
Medicine (Baltimore). 2020 Dec 4;99(49):e23531. doi: 10.1097/MD.0000000000023531.
Percutaneous endoscopic interlaminar discectomy (PEID) has been widely used in the treatment of lumbar disc herniation and spinal stenosis, epidural steroids following PEID in an effort to reduce the incidence and duration of postoperative pain. Although steroids are widely thought to reduce the effect of surgical trauma, the observation index is not uniform, so the issue is still controversial. Therefore, the purpose of this paper is to systematically evaluate the efficacy and safety of local epidural steroids application following PEID.
We will search the following databases from their inception to August 2020, PubMed, Embase, Medline, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database, Web of Science, Wan Fang Database, Cochrane Library. The search strategy includes the MeSH terms. Meta-analysis will be performed using Rev Man V.5.3.5 statistical software.
This study will provide a high-quality synthesis to evaluate the efficacy and safety of local epidural steroids following PEID.
This systematic review will provide evidence to judge whether local epidural steroids application following PEID is an effective and safe intervention for patients. It will provide reliable evidence for its extensive application.
INPLASY2020100085.
经皮内镜椎间孔切开椎间盘切除术（PEID）已广泛应用于腰椎间盘突出症和椎管狭窄症的治疗，PEID术后使用硬膜外类固醇以降低术后疼痛的发生率和持续时间。尽管普遍认为类固醇可减轻手术创伤的影响，但观察指标并不统一，因此该问题仍存在争议。因此，本文旨在系统评价PEID术后局部应用硬膜外类固醇的疗效和安全性。
我们将检索以下数据库自建库至2020年8月的数据，包括PubMed、Embase、Medline、中国知网、中国生物医学文献数据库、Web of Science、万方数据库、Cochrane图书馆。检索策略包括医学主题词。将使用Rev Man V.5.3.5统计软件进行荟萃分析。
本研究将提供高质量的综合分析，以评估PEID术后局部应用硬膜外类固醇的疗效和安全性。
本系统评价将为判断PEID术后局部应用硬膜外类固醇对患者是否为有效且安全的干预措施提供证据。它将为其广泛应用提供可靠依据。
INPLASY2020100085。
