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与水痘-带状疱疹病毒和弓形虫合并感染相关的虹彩萎缩的白色圆形斑点模式:病例报告。

A white circular-spot pattern of iridian atrophy associated with Varicella-zoster virus and Toxoplasma gondii coinfection: a case report.

机构信息

Escuela Barraquer. Research Group, Escuela Superior de Oftalmología - Instituto Barraquer de América, Avenida Calle 100 # 18A - 51, Bogotá, Colombia.

NeURos Research Group, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Carrera 24 # 63 C 69, Bogotá, Colombia.

出版信息

BMC Ophthalmol. 2020 Dec 7;20(1):479. doi: 10.1186/s12886-020-01748-8.

Abstract

BACKGROUND

We report a case of white circular spots of iridian atrophy, which we will call "polka dots" pattern, as a rare ophthalmological finding associated with uveitis secondary to varicella-zoster virus and Toxoplasma gondii coinfection in a male patient in Bogotá, Colombia.

CASE PRESENTATION

We present de case of a 53-year-old Colombian male patient with a diagnosis of anterior uveitis in his left eye due to varicella-zoster virus and Toxoplasma gondii coinfection documented by polymerase chain reaction analysis. He presented with multiple areas of superficial white circular spots of iridian atrophy in 360º, some with deeper atrophy where the stroma fibers were visualized and only a small punctate defect of transillumination was evident. This rare pattern of iridian atrophy has not been previously described in cases of uveitis in the literature.

CONCLUSIONS

This is the first case reporting the findings of superficial "polka dots" pattern iridian atrophy in 360° secondary to anterior uveitis due to the coinfection of a virus and a parasite. The identification of similar clinical cases may lead to early initiation of systemic treatment in these patients.

摘要

背景

我们报告了一例虹膜萎缩的白色圆形斑点,我们将其称为“波尔卡 dots”模式,这是一种罕见的眼科发现,与哥伦比亚波哥大的一名男性患者的水痘带状疱疹病毒和弓形虫合并感染引起的葡萄膜炎有关。

病例介绍

我们介绍了一名 53 岁的哥伦比亚男性患者,他因水痘带状疱疹病毒和弓形虫合并感染,经聚合酶链反应分析确诊为左眼前葡萄膜炎。他的左眼 360°出现多个浅层白色圆形虹膜萎缩斑点,有些部位较深,可见基质纤维,仅隐约可见一个小点状透光缺陷。这种虹膜萎缩的罕见模式以前在文献中报道的葡萄膜炎病例中没有出现过。

结论

这是首例报告由于病毒和寄生虫合并感染引起的前葡萄膜炎导致的 360°浅层“波尔卡 dots”模式虹膜萎缩的病例。类似临床病例的识别可能会导致这些患者早期开始全身治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbc/7720502/24968c625596/12886_2020_1748_Fig1_HTML.jpg

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