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[气管插管期间斜坡位与嗅物位的比较:一项系统评价和荟萃分析]

[A comparison of ramping position and sniffing position during endotracheal intubation: a systematic review and meta-analysis].

作者信息

Tsan Samuel Ern Hung, Ng Ka Ting, Lau Jiaying, Viknaswaran Navian Lee, Wang Chew Yin

机构信息

Departamento de Anestesiologia, Faculty of Medicine and Health Sciences, University of Malaysia Sarawak, Sarawak, Malásia.

Departamento de Anestesiologia, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malásia.

出版信息

Braz J Anesthesiol. 2020 Nov-Dec;70(6):667-677. doi: 10.1016/j.bjan.2020.08.009. Epub 2020 Nov 9.

Abstract

OBJECTIVES

Positioning during endotracheal intubation (ETI) is critical to ensure its success. We aimed to determine if the ramping position improved laryngeal exposure and first attempt success at intubation when compared to the sniffing position.

METHODS

PubMed, EMBASE, and Cochrane CENTRAL databases were searched systematically from inception until January 2020. Our primary outcomes included laryngeal exposure as measured by Cormack-Lehane Grade 1 or 2 (CLG 1/2), CLG 3 or 4 (CLG 3/4), and first attempt success at intubation. Secondary outcomes were intubation time, use of airway adjuncts, ancillary maneuvers, and complications during ETI.

RESULTS

Seven studies met our inclusion criteria, of which 4 were RCTs and 3 were cohort studies. The meta-analysis was conducted by pooling the effect estimates for all 4 included RCTs (n = 632). There were no differences found between ramping and sniffing positions for odds of CLG 1/2, CLG 3/4, first attempt success at intubation, intubation time, use of ancillary airway maneuvers, and use of airway adjuncts, with evidence of high heterogeneity across studies. However, the ramping position in surgical patients is associated with increased likelihood of CLG 1/2 (OR = 2.05, 95% CI 1.26 to 3.32, = 0.004) and lower likelihood of CLG 3/4 (OR = 0.49, 95% CI 0.30 to 0.79, = 0.004), moderate quality of evidence.

CONCLUSION

Our meta-analysis demonstrated that the ramping position may benefit surgical patients undergoing ETI by improving laryngeal exposure. Large scale well designed multicentre RCTs should be carried out to further elucidate the benefits of the ramping position in the surgical and intensive care unit patients.

摘要

目的

气管插管(ETI)期间的体位对于确保插管成功至关重要。我们旨在确定与嗅探位相比,斜坡位是否能改善喉镜视野暴露及首次插管尝试的成功率。

方法

系统检索了PubMed、EMBASE和Cochrane CENTRAL数据库,检索时间从建库至2020年1月。我们的主要结局包括采用Cormack-Lehane 1级或2级(CLG 1/2)、CLG 3级或4级(CLG 3/4)评估的喉镜视野暴露情况以及首次插管尝试的成功率。次要结局包括插管时间、气道辅助工具的使用、辅助操作以及ETI期间的并发症。

结果

七项研究符合我们的纳入标准,其中四项为随机对照试验(RCT),三项为队列研究。通过汇总所有四项纳入的RCT(n = 632)的效应估计值进行荟萃分析。在CLG 1/2、CLG 3/4的发生率、首次插管尝试成功率、插管时间、辅助气道操作的使用以及气道辅助工具的使用方面,斜坡位和嗅探位之间未发现差异,各研究间存在高度异质性。然而,手术患者采用斜坡位与CLG 1/2发生率增加(OR = 2.05,95% CI 1.26至3.32,P = 0.004)及CLG 3/4发生率降低(OR = 0.49,95% CI 0.30至0.79,P = 0.004)相关,证据质量中等。

结论

我们的荟萃分析表明,斜坡位可能通过改善喉镜视野暴露而使接受ETI的手术患者受益。应开展大规模、设计良好的多中心RCT,以进一步阐明斜坡位在手术患者和重症监护病房患者中的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2251/9373499/6e5ade87e020/gr1.jpg

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