3-D Large-Pitch Synthetic Transmit Aperture Imaging With a Reduced Number of Measurement Channels: A Feasibility Study.

A 3-D synthetic transmit aperture ultrasound imaging system with a fully addressed array usually leads to high hardware complexity and cost since each element in the array is individually controlled. To reduce the hardware complexity, we had presented the large-pitch synthetic transmit aperture (LPSTA) ultrasound imaging for 2-D imaging using a 1-D phased array to reduce the number of measurement channels M (the product of number of transmissions, [Formula: see text], and the number of receiving channels in each transmission, [Formula: see text]). In this article, we extend this method to a 2-D matrix array for 3-D imaging. We present both numerical simulations and experimental measurements. We combined L × L adjacent elements into transmission subapertures (SAP) and K × K adjacent elements into receive SAPs in synthetic transmit aperture (STA) imaging. In the image reconstruction, we conducted the first attempt to apply and integrate Gaussian-approximated spatial response function (G-SRF) with delay and sum (DAS) to improve the image contrast, especially for the near-field targets. The imaging performance obtained from G-SRF was also evaluated numerically and compared with the previously presented frequency-domain SRF (Freq-domain SRF). The 3-D large-pitch synthetic transmit aperture (3-D-LPSTA) with G-SRF can provide a computationally efficient solution compared with the standard 3-D-STA method. With approximately 1900-fold reduction in the number of measurement channels, 3-D-LPSTA can provide image contrast comparable with the standard 3-D-STA with a full array and significantly better than using a periodically sparse array with similar complexity. In addition to reducing the system complexity, the 3-D-LPSTA achieves 700-fold reduction in computational complexity and 523-fold reduction in data storage. Finally, we evaluated and implemented the G-SRF using phantom data, which were consistent with the simulation results showing that the G-SRF can improve the image contrast. The results demonstrate that the proposed 3-D-LPSTA shows the great potential for designing an inexpensive ultrasound system to ensure the real-time 3-D clinical ultrasound imaging using large arrays. The limits of the proposed method were also discussed.