Department of Otolaryngology, Galilee Medical Center, Nahariya, Israel; The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
The Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Int J Pediatr Otorhinolaryngol. 2021 Jan;140:110534. doi: 10.1016/j.ijporl.2020.110534. Epub 2020 Nov 30.
Acute otitis externa (AOE), is a common infectious disease affecting children and adults. Its peak prevalence is around the summer months, it involves the external auditory canal and in most cases is due to bacterial agents.
This is a retrospective observational analytical case-based study involving all consecutive patients under the age of 18 years old presenting with AOE to a pediatric emergency department.
We collected data from 337 patients under 18 years of age with 344 visits to the Emergency Department, between the years 2011-2018. Nearly half of the visits presented during the summer months. Children were divided into two subgroups: hospitalized and non-hospitalized. Median hospitalization time was 3 days. The hospitalized sub-group had higher rates of failed treatment, as well as higher rates of external ear canal edema, systemic fever, canal discharge and auricular edema. On multivariable analysis the following variables had the strongest correlation for hospital admission: auricular edema (OR 27.98), otorrhea (OR 1.82), narrowing of the ear canal by more than 50% (OR 1.91), fever (OR 2.92), and previous systemic treatment (OR 2.53). Pseudomonas aeruginosa (PA) was isolated in 78% of cultures in the hospitalized sub-group. All PA strains were sensitive to ciprofloxacin.
This study highlights the main clinical variables which may predict hospitalization among children with AOE as well as the dominant role of sensitive strains of PA in the pathogenesis of this condition in children.
急性外耳炎(AOE)是一种常见的传染病,影响儿童和成人。其高发期在夏季,涉及外耳道,在大多数情况下是由细菌引起的。
这是一项回顾性观察分析病例对照研究,涉及所有在儿科急诊就诊的年龄在 18 岁以下的连续 AOE 患者。
我们收集了 2011 年至 2018 年间 337 名年龄在 18 岁以下的患者在急诊科就诊的 344 次就诊的数据。近一半的就诊发生在夏季。儿童分为住院和非住院两组。住院时间中位数为 3 天。住院组治疗失败率较高,且外耳道水肿、全身发热、耳道分泌物和耳廓水肿发生率较高。多变量分析显示,以下变量与住院相关性最强:耳廓水肿(OR 27.98)、耳漏(OR 1.82)、耳道狭窄超过 50%(OR 1.91)、发热(OR 2.92)和先前的全身治疗(OR 2.53)。住院组的 78%的培养物中分离出铜绿假单胞菌(PA)。所有 PA 株均对环丙沙星敏感。
本研究强调了可能预测儿童 AOE 住院的主要临床变量,以及敏感 PA 株在外耳道炎发病机制中的主导作用。