Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul 138-736, The Republic of Korea.
Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul 138-736, The Republic of Korea
Br J Ophthalmol. 2022 Apr;106(4):485-490. doi: 10.1136/bjophthalmol-2020-317850. Epub 2020 Dec 8.
BACKGROUND/AIMS: To compare the structure-function relationship between compass microperimetry (CMP; CenterVue, Padova, Italy) and Humphrey field analyser (HFA; Carl Zeiss Meditec, Dublin, California, USA) in open-angle glaucoma (OAG) eyes with myopia.
Circumpapillary retinal nerve fibre layer thickness (cpRNFLT) and visual field (VF) mean sensitivity (MS) were obtained in 90 OAG subjects using the optical coherence tomography, CMP and HFA in a random order. The global and sectoral structure-function relationships between the cpRNFLT and VFMS were assessed with different VF devices (CMP vs HHA) in OAG eyes with and without myopia.
Overall, the global and regional structure-function relationships between the two devices did not show significant differences except for the superotemporal sector. In the myopic subgroup, the global association between the average cpRNFLT and VFMS was significantly stronger than that between the average cpRNFLT and VFMS (r=0.806 vs. 0.720, p=0.035). The presence of myopia and higher global cpRNFLT were significantly associated with the greater global VFMS differences between the two devices (p<0.05).
In general, structure-function relationship is similar between CMP and HFA in OAG eyes. However, the global structure-function relationship is significantly stronger with CMP than with HFA in OAG eyes with myopia.
背景/目的：比较在伴有近视的开角型青光眼（OAG）眼中，罗盘微视野计（CMP；意大利帕多瓦 CenterVue）和 Humphrey 视野分析仪（HFA；美国加利福尼亚州都柏林 Carl Zeiss Meditec）的结构-功能关系。
使用光学相干断层扫描、CMP 和 HFA 以随机顺序对 90 例 OAG 患者的周边视网膜神经纤维层厚度（cpRNFLT）和视野（VF）平均敏感度（MS）进行测量。在伴有和不伴有近视的 OAG 眼中，使用不同的 VF 设备（CMP 与 HFA）评估 cpRNFLT 和 VFMS 之间的全局和扇形结构-功能关系。
总体而言，两种设备之间的全局和区域结构-功能关系除了超颞部扇形区外，没有显著差异。在近视亚组中，平均 cpRNFLT 与 VFMS 之间的全局相关性明显强于平均 cpRNFLT 与 VFMS 之间的相关性（r=0.806 与 0.720，p=0.035）。存在近视和较高的全球 cpRNFLT 与两种设备之间更大的全球 VFMS 差异显著相关（p<0.05）。
一般来说，CMP 和 HFA 在 OAG 眼中的结构-功能关系相似。然而，在伴有近视的 OAG 眼中，CMP 的全局结构-功能关系明显强于 HFA。
