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童年逆境与中老年期的多种疾病轨迹:中国健康与养老追踪调查

Childhood adversity and trajectories of multimorbidity in mid-late life: China health and longitudinal retirement study.

作者信息

Yang Lei, Hu Yaoyue, Silventoinen Karri, Martikainen Pekka

机构信息

School of Ethnology and Sociology, Minzu University of China, Beijing, China.

School of Public Health and Management, Chongqing Medical University, Chongqing, China

出版信息

J Epidemiol Community Health. 2020 Dec 8. doi: 10.1136/jech-2020-214633.

Abstract

BACKGROUND

The association between childhood adversity and an individual's health in later life has been extensively studied in Western societies; however, little is known about this association for the development of multimorbidity in China.

METHODS

Three waves (2011-2012, 2013 and 2015) of the China Health and Retirement Longitudinal Study were used for adults aged 45-101 years. Multimorbidity was assessed by the summed scores of self-reported physician diagnoses of 14 chronic diseases. Childhood adversity was measured by the incidence of childhood abuse and neglect, negative caregiver's characteristics and low socioeconomic status. Latent growth curve modelling was used to investigate the trajectory of multimorbidity by childhood adversity.

RESULTS

Parental physical abuse was associated with increased number of chronic diseases (intercept: 0.119; 95% CI: 0.033 to 0.205 for men and 0.268: 95% CI: 0.188 to 0.348 for women) and a higher rate of increase (slope: 0.013: 95% CI: 0.000 to 0.027 for men and 0.022: 95% CI: 0.008 to 0.036 for women) in multimorbidity. Adequacy of food was associated with a lower number chronic diseases at baseline (men: -0.171: 95% CI: -0.245 to -0.097; women: -0.223: 95% CI: -0.294 to -0.152) and a slower rate of change in multimorbidity (men: -0.015 per year: 95% CI: -0.027 to -0.003; women: -0.012 per year: 95% CI: -0.024 to -0.001).

CONCLUSIONS

The results demonstrate that childhood adversity exerts long-lasting effects on multimorbidity among older adults in China. Prevention of childhood maltreatment may delay or even avert the emergence of multimorbidity in later life.

摘要

背景

西方社会广泛研究了童年逆境与个体晚年健康之间的关联;然而,对于中国多重疾病发生发展的这种关联却知之甚少。

方法

中国健康与养老追踪调查的三个阶段(2011 - 2012年、2013年和2015年)数据用于45 - 101岁的成年人。多重疾病通过自我报告医生诊断的14种慢性病的总分来评估。童年逆境通过童年期虐待和忽视的发生率、负面照料者特征以及低社会经济地位来衡量。采用潜在增长曲线模型研究童年逆境对多重疾病发展轨迹的影响。

结果

父母身体虐待与慢性病数量增加相关(截距:男性为0.119;95%置信区间:0.033至0.205;女性为0.268;95%置信区间:0.188至0.348)以及多重疾病发生率更高(斜率:男性为0.013;95%置信区间:0.000至0.027;女性为0.022;95%置信区间:0.008至0.036)。食物充足与基线时慢性病数量较少相关(男性:-0.171;95%置信区间:-0.245至-0.097;女性:-0.223;95%置信区间:-0.294至-0.152)以及多重疾病变化率较慢(男性:每年-0.015;95%置信区间:-0.027至-0.003;女性:每年-0.012;95%置信区间:-0.024至-0.001)。

结论

结果表明童年逆境对中国老年人的多重疾病产生长期影响。预防童年期虐待可能会延缓甚至避免晚年多重疾病的出现。

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