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特发性自发性盲肠穿孔:一种死亡率高的罕见病理情况。

Idiopathic spontaneous cecal perforation: A rare pathology with high mortality.

作者信息

Al-Balas Hamzeh, Al-Balas Mahmoud, Al-Wiswasy Mohammad

机构信息

Department of General and Special Surgery, Faculty of Medicine, Hashemite University, Jordan.

Department of Surgery, Prince Hamza Hospital, Amman, Jordan.

出版信息

Ann Med Surg (Lond). 2020 Nov 21;60:518-521. doi: 10.1016/j.amsu.2020.11.047. eCollection 2020 Dec.

DOI:10.1016/j.amsu.2020.11.047
PMID:33294185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7695924/
Abstract

INTRODUCTION

Spontaneous perforation of the colon (SPC) is a rare disease characterized by sudden perforation of a clinically healthy colon in the absence of underlying disease or trauma. The aim of reporting this case is to highlight this surgical emergency in terms of clinical presentations, surgical management and outcomes.

PRESENTATION OF CASE

A 68 year-old male with history of diabetes mellitus, hypertension and chronic constipation on daily laxatives presented to the emergency department with a diffuse abdominal pain and distention for 4 days associated with vomiting and absence of defecation where he was prescribed phosphate rectal enemas. Patient was in sepsis with generalized abdominal tenderness and distention. Intraoperative findings of feculent peritonitis with isolated cecal perforation was identified, for which a right hemicolectomy with end ileostomy was performed.

DISCUSSION

The first case was described in a woman presented with spontaneous rectum rupture by Brodie in 1827, with a less than 100 cases being reported in literature. In 1984, spontaneous perforations were classified into either "stercoral" or "idiopathic" perforations. More than 60% of colonic perforations were reported in the sigmoid or at the recto-sigmoid junction, mainly at the anti-mesenteric border, making spontaneous cecal perforation a very uncommon condition. Cecal perforation is associated with high mortality in the range of 30%-72%.

CONCLUSION

The outcome of SPC depends on multiple factors like onset of perforation, peritoneal contamination, and time of intervention. Regardless the surgical technique, early detection and surgical management are the main strategies associated with improving the outcomes.

摘要

引言

结肠自发性穿孔(SPC)是一种罕见疾病,其特征为临床健康的结肠在无潜在疾病或创伤的情况下突然穿孔。报告该病例的目的是在临床表现、手术治疗及预后方面突出这种外科急症。

病例介绍

一名68岁男性,有糖尿病、高血压病史,因慢性便秘每日服用泻药,因弥漫性腹痛、腹胀4天,伴有呕吐及无排便而就诊于急诊科,在急诊科接受了磷酸直肠灌肠治疗。患者处于脓毒症状态,全腹压痛、腹胀。术中发现粪性腹膜炎伴孤立性盲肠穿孔,遂行右半结肠切除术加末端回肠造口术。

讨论

首例病例由布罗迪于1827年描述,为一名出现自发性直肠破裂的女性,文献报道的病例不足100例。1984年,自发性穿孔被分为“粪性”或“特发性”穿孔。超过60%的结肠穿孔发生在乙状结肠或直肠乙状结肠交界处,主要位于系膜对侧缘,因此自发性盲肠穿孔是一种非常罕见的情况。盲肠穿孔的死亡率较高,在30%-72%之间。

结论

SPC的预后取决于穿孔的发生、腹腔污染及干预时间等多种因素。无论采用何种手术技术,早期发现及手术治疗是改善预后的主要策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e8/7695924/b9374c0cd734/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e8/7695924/5e9563c2e54a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e8/7695924/b9374c0cd734/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e8/7695924/5e9563c2e54a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5e8/7695924/b9374c0cd734/gr2.jpg

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本文引用的文献

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The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2018 声明:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2018 Dec;60:132-136. doi: 10.1016/j.ijsu.2018.10.028. Epub 2018 Oct 18.
2
Spontaneous cecal perforation in a 40-year-old pregnant woman treated by primary repair and omental patch: a case report.40岁孕妇自发性盲肠穿孔经一期修补和网膜补片治疗:一例报告
J Med Case Rep. 2017 Jun 18;11(1):162. doi: 10.1186/s13256-017-1336-x.
3
An Unusual Cause of Right Iliac Fossa Pain: Caecal Diverticulum Perforation.
右髂窝疼痛的罕见原因:盲肠憩室穿孔。
J Coll Physicians Surg Pak. 2015 Oct;25 Suppl 2:S115-6. doi: 10.2015/JCPSP.S411S116.
4
Spontaneous perforation of the colon clinical review of five episodes in four patients.结肠自发性穿孔:4例患者5次发作的临床回顾
Oman Med J. 2009 Apr;24(2):137-41. doi: 10.5001/omj.2009.30.
5
Appendicular perforation at the base of the caecum, a rare operative challenge in acute appendicitis, a literature review.盲肠底部阑尾穿孔,急性阑尾炎手术的罕见挑战,文献复习。
World J Emerg Surg. 2011 Nov 4;6:36. doi: 10.1186/1749-7922-6-36.
6
Cecal perforation due to paralytic ileus following primary caesarean section.初次剖宫产术后因麻痹性肠梗阻导致的盲肠穿孔
J Obstet Gynaecol Can. 2009 Feb;31(2):167-71. doi: 10.1016/s1701-2163(16)34102-0.
7
Diagnosis and treatment of spontaneous colonic perforation: analysis of 10 cases.自发性结肠穿孔的诊断与治疗:10例分析
World J Gastroenterol. 2008 Jul 28;14(28):4569-72. doi: 10.3748/wjg.14.4569.
8
Use of accurate diagnostic criteria may increase incidence of stercoral perforation of the colon.使用准确的诊断标准可能会增加结肠粪性穿孔的发生率。
Dis Colon Rectum. 2000 Jul;43(7):991-8. doi: 10.1007/BF02237366.
9
Idiopathic perforation of the sigmoid colon in Japan.日本乙状结肠特发性穿孔
World J Surg. 1981 Jan;5(1):125-30. doi: 10.1007/BF01657857.
10
Stercoral perforation of the colon.结肠粪性穿孔
Br J Surg. 1990 Dec;77(12):1325-9. doi: 10.1002/bjs.1800771204.