Ben Ismail Imen, Sghaier Marwen, Rebii Saber, Manai Ghazi, Zoghlami Ayoub
University of Tunis El Manar, Department of General Surgery, Trauma Center Ben Arous, Tunisia.
University of Tunis El Manar, Department of General Surgery, Trauma Center Ben Arous, Tunisia.
Int J Surg Case Rep. 2024 Oct;123:110313. doi: 10.1016/j.ijscr.2024.110313. Epub 2024 Sep 18.
Stercoral perforation of the colon is a rare and life-threatening condition caused by pressure necrosis due to fecal impaction. It is commonly associated with chronic constipation, particularly in patients with neurogenic bowel disorders or prolonged opioid use. However, its occurrence in the context of chronic heroin use is rarely reported.
We report the case of a 40-year-old male with a 5-year history of heroin abuse who presented with diffuse abdominal pain, vomiting, and cessation of gas and stool passage for 10 days. Physical examination revealed a distended abdomen with generalized tenderness, guarding, and a rectal examination confirmed fecal impaction. Computed tomography (CT) showed massive fecal impaction in the sigmoid colon with pneumoperitoneum, indicating perforation. The patient underwent urgent exploratory laparotomy, revealing two perforations in the sigmoid colon with extensive fecal peritonitis. A segmental resection of the sigmoid colon with colostomy was performed. Postoperatively, the patient required intensive care for septic shock but eventually recovered and was referred to an addiction treatment program.
This case highlights the serious gastrointestinal complications associated with chronic opioid use, particularly heroin. The pathophysiology involves opioid-induced inhibition of gastrointestinal motility, leading to chronic constipation, fecaloma formation, and subsequent perforation. Early recognition and prompt surgical intervention are crucial in managing stercoral perforation, which carries a high mortality rate if delayed.
This case underscores the importance of recognizing gastrointestinal risks in chronic opioid users, especially heroin, and the need for integrated care strategies to prevent severe complications like stercoral perforation.
结肠粪性穿孔是一种罕见且危及生命的疾病,由粪块嵌塞导致的压力性坏死引起。它通常与慢性便秘相关,尤其是在患有神经源性肠病或长期使用阿片类药物的患者中。然而,在慢性海洛因使用背景下其发生情况鲜有报道。
我们报告一例40岁男性,有5年海洛因滥用史,出现弥漫性腹痛、呕吐,且停止排气排便10天。体格检查发现腹部膨隆,有广泛压痛、肌紧张,直肠指检证实有粪块嵌塞。计算机断层扫描(CT)显示乙状结肠有大量粪块嵌塞并伴有气腹,提示穿孔。患者接受了紧急剖腹探查术,发现乙状结肠有两处穿孔并伴有广泛的粪性腹膜炎。进行了乙状结肠节段性切除并造口术。术后,患者因感染性休克需要重症监护,但最终康复,并被转至戒毒治疗项目。
该病例突出了与慢性阿片类药物使用,尤其是海洛因相关的严重胃肠道并发症。其病理生理过程包括阿片类药物引起的胃肠动力抑制,导致慢性便秘、粪块形成及随后的穿孔。早期识别和及时的手术干预对于处理粪性穿孔至关重要,若延误治疗,其死亡率很高。
该病例强调了认识慢性阿片类药物使用者,尤其是海洛因使用者胃肠道风险的重要性,以及采取综合护理策略以预防粪性穿孔等严重并发症的必要性。