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双磷酸盐在原发性甲状旁腺功能亢进术后饥饿骨综合征预防中的作用：一项荟萃分析和随机对照试验的需求。

Role of Bisphosphonates in The Prevention of Postoperative Hungry Bone Syndrome in Primary Hyperparathyroidism: A Meta-Analysis and Need for Randomized Controlled Trials.

出版信息

Drug Res (Stuttg). 2021 Feb;71(2):108-109. doi: 10.1055/a-1325-0351. Epub 2020 Dec 9.

DOI:10.1055/a-1325-0351
PMID:33296924
Abstract

Dear Editor,Hungry bone syndrome (HBS) is a clinico-biochemical entity characterized by the development of profound and prolonged hypocalcemia associated with hypophosphatemia, hypomagnesemia, and rising alkaline phosphatase which follows curative parathyroidectomy for severe primary and secondary hyperparathyroidism. The prevalence of HBS after parathyroidectomy in primary hyperparathyroidism (PHPT) is variable with several case series from Asia reporting remarkably higher prevalence rates of 24-87% 1.

摘要

致编辑

饥饿骨综合征（HBS）是一种临床生物化学实体，其特征是在治愈性甲状旁腺切除术后，严重原发性和继发性甲状旁腺功能亢进症患者出现严重和持久的低钙血症，并伴有低磷血症、低镁血症和碱性磷酸酶升高。甲状旁腺切除术后原发性甲状旁腺功能亢进症（PHPT）中 HBS 的发生率存在差异，亚洲的几项病例系列报告显示，HBS 的发生率明显更高，为 24-87%1。

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