早老性痴呆的立体定向脑活检

Stereotactic brain biopsies in presenile dementia.

作者信息

Waltregny A, Abdul Maula A, Brucher J M

机构信息

Neurosurgical Department, University of Liège, Belgium.

出版信息

Appl Neurophysiol. 1987;50(1-6):218-22. doi: 10.1159/000100712.

DOI:10.1159/000100712

PMID:3329849

Abstract

Early detection and precise diagnosis of presenile dementias are important since they determine subsequent medical care. Presently the only way to classify these syndromes is by neuropathological examination. Between 1972 and 1987, 222 stereotactic serial brain biopsies were performed in 25 selected demented patients. Comparison between preoperative clinical diagnosis and histological finding gives the following results: in 32% the clinical diagnosis has been confirmed, in 60% the diagnosis has been corrected or specified and in 8% the stereotactic brain biopsies only showed unspecific pathological gliosis.

摘要

早老性痴呆的早期发现和精确诊断很重要，因为它们决定了后续的医疗护理。目前，对这些综合征进行分类的唯一方法是通过神经病理学检查。1972年至1987年间，对25名选定的痴呆患者进行了222次立体定向连续脑活检。术前临床诊断与组织学检查结果对比得出以下结果：32%的临床诊断得到证实，60%的诊断得到纠正或明确，8%的立体定向脑活检仅显示非特异性病理性胶质增生。