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病例报告:新型冠状病毒2019感染中的肾性钾消耗

Case Report: Renal potassium wasting in SARS-CoV-2 infection.

作者信息

Mabillard Holly, Tedd Hilary, Speight Ally, Duncan Christopher, Price David A, Sayer John A

机构信息

Renal Services, The Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, Tyne and Wear, NE77DN, UK.

Department of Respiratory Medicine, The Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, Tyne and Wear, NE14LP, UK.

出版信息

F1000Res. 2020 Jun 30;9:659. doi: 10.12688/f1000research.24621.2. eCollection 2020.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with many potentially fatal complications. Renal involvement in various forms is common in addition to serum electrolyte disturbances. Early reports suggest that hypokalaemia may frequent those with SARS-CoV-2 infection and various aetiological factors may cause this electrolyte disturbance. A Chinese retrospective study has demonstrated renal potassium wasting in patients infected with SARS-CoV-2, however, it is not known if these patients were receiving diuretic therapy which may be a contributing factor. This case report illustrates an example of renal potassium wasting in SARS-CoV-2 infection in the absence of diuretics and extra-renal mechanisms with important lessons learned.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染与许多潜在的致命并发症相关。除血清电解质紊乱外,各种形式的肾脏受累也很常见。早期报告表明,低钾血症在SARS-CoV-2感染患者中可能很常见,各种病因可能导致这种电解质紊乱。一项中国的回顾性研究表明,感染SARS-CoV-2的患者存在肾性钾消耗,然而,尚不清楚这些患者是否接受了可能是一个促成因素的利尿剂治疗。本病例报告举例说明了在没有利尿剂和肾外机制的情况下,SARS-CoV-2感染中肾性钾消耗的情况,并从中吸取了重要教训。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dba/7702305/d5d1c10b92c7/f1000research-9-30666-g0000.jpg

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