Ruppert Lisa Marie, Reilly Julia
Rehabilitation Medicine Service, Department of Neurology, Memorial Sloan Kettering Cancer Center; New York, NY.
Department of Rehabilitation Medicine, Weill Cornell Medical Center; New York, NY.
Neurooncol Pract. 2020 Nov 18;7(Suppl 1):i54-i61. doi: 10.1093/nop/npaa058. eCollection 2020 Nov.
Spinal tumors pose significant treatment challenges for the physicians treating them. Understanding the location of the tumor within the intramedullary, intradural extramedullary, or extradural (epidural) space is not only critical in determining a differential diagnosis but may also provide important information about current and future neurologic deficits. Despite significant advances in the treatment of spinal tumors over the past few decades, these patients may still experience significant symptoms related to the tumor or its treatment, such as pain, weakness, impaired sensation, and bowel and bladder dysfunction. Treatment of spinal tumors should involve a multidisciplinary team of neuro-oncologists, spine surgeons, medical and radiation oncologists, physiatrists, and pain specialists to provide comprehensive oncologic management, while optimizing the patient's functional status and quality of life.
脊柱肿瘤给治疗它们的医生带来了重大的治疗挑战。了解肿瘤在髓内、硬脊膜内髓外或硬脊膜外(硬膜外)空间的位置,不仅对于确定鉴别诊断至关重要,还可能提供有关当前和未来神经功能缺损的重要信息。尽管在过去几十年中脊柱肿瘤的治疗取得了重大进展,但这些患者仍可能经历与肿瘤或其治疗相关的严重症状,如疼痛、虚弱、感觉受损以及肠道和膀胱功能障碍。脊柱肿瘤的治疗应包括神经肿瘤学家、脊柱外科医生、医学和放射肿瘤学家、物理治疗师和疼痛专家组成的多学科团队,以提供全面的肿瘤管理,同时优化患者的功能状态和生活质量。