Economou-Stamatelopoulou C, Papavassiliou J
Université Nationale d'Athènes, Faculté de Médecine, Laboratoire de Microbiologie, Grèce.
Bull Soc Pathol Exot Filiales. 1987;80(5):751-5.
Twenty disinfectants were tested against a strain of K. pneumoniae. A suspension test with incremental addition of microorganisms was used. The influence of interfering substances (proteins and hard water) on the activity of disinfectants was also determined. Iodine compounds were influenced by proteins in distilled and hard water. The presence of mineral ions inactivated the polyvinylpyrrolidone-iodine 10% and chloroxylenol preparations against K. pneumoniae. The activity of some iodine products disappeared at the second and third incremental addition of microorganisms; the chloroxylenol and the phenolic compounds were inactivated by proteins at the third incremental addition. The sensibility of K. pneumoniae to the other disinfectants was not influenced by proteins, ions and incremental bacterial additions.
对20种消毒剂针对一株肺炎克雷伯菌进行了测试。采用了微生物逐步添加的悬液试验。还测定了干扰物质（蛋白质和硬水）对消毒剂活性的影响。碘化合物在蒸馏水和硬水中受蛋白质影响。矿物离子的存在使10%聚乙烯吡咯烷酮碘制剂和对氯二甲苯酚制剂对肺炎克雷伯菌失去活性。在微生物第二次和第三次逐步添加时，一些碘产品的活性消失；在第三次逐步添加时，对氯二甲苯酚和酚类化合物被蛋白质灭活。肺炎克雷伯菌对其他消毒剂的敏感性不受蛋白质、离子和细菌逐步添加的影响。
