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[在马约特岛开展的乙胺嗪群体化疗运动对班氏吴策线虫血液微丝蚴的疗效]

[Effectiveness of mass chemotherapy campaigns with diethylcarbamazine on blood microfilaria of Wuchereria bancrofti in Mayotte].

作者信息

Galtier J, Julvez J, Michault A, Isautier H

机构信息

Médecin-Inspecteur de la Santé, Mamoudzou, Mayotte.

出版信息

Bull Soc Pathol Exot Filiales. 1987;80(5):826-33.

PMID:3329988
Abstract

An evaluation of the microfilarial index has been carried out in a randomised population, during April and May 1986, to determine the efficacy of long course mass chemotherapy. A single dose of DEC at 6 mg/kg was distributed to the whole population of the island, every 4 months, in 1985 and 1986. The survey was done three months after the treatment. 1,307 thick blood films have been collected in night-time. The prevalence of microfilaremia was 1.9% as compared with 17.1% in 1981 in the conditions. The control measures were considered as quite satisfactory, and it was decided to continue mass chemotherapy together with vector control.

摘要

1986年4月至5月期间,在一个随机抽样的人群中对微丝蚴指数进行了评估,以确定长期大规模化疗的疗效。1985年和1986年,每4个月向该岛全体居民分发一次剂量为6毫克/千克的单剂量乙胺嗪。调查在治疗三个月后进行。夜间采集了1307份厚血膜。微丝蚴血症患病率为1.9%,而在当时的情况下,1981年为17.1%。控制措施被认为相当令人满意,因此决定继续进行大规模化疗并结合病媒控制。

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