Teixeira Elisabete, Soares Paula
Faculdade de Medicina da Universidade do Porto (FMUP).
Instituto de Investigação e Inovação em Saúde (i3S).
Porto Biomed J. 2020 Dec 3;5(6):e107. doi: 10.1097/j.pbj.0000000000000107. eCollection 2020 Nov-Dec.
Hypertension (HT) is a prevalent disease, which origin frequently remains undetermined. Antihypertensive treatment (AHT) has been linked with erectile dysfunction (ED), mainly in middle-aged and older males. On the other side, some drugs used in AHT seem to be themselves associated with ED as a secondary effect. This led to the search of coadjuvant therapies for hypertensive patients with ED, considering that both illnesses cause high physical, psychological and economic burden. While the association between AHT and ED has been approached several times, the direct association between blood pressure and ED remains unclear. This review aims to summarize the current knowledge on the relationship between HT, AHT and ED specifically in males with age ≥40 years.
高血压(HT)是一种常见疾病,其病因常常不明。抗高血压治疗(AHT)与勃起功能障碍(ED)有关,主要发生在中老年男性中。另一方面,AHT中使用的一些药物本身似乎也会导致ED这一副作用。鉴于这两种疾病都会造成较高的身体、心理和经济负担,因此人们开始寻找针对患有ED的高血压患者的辅助治疗方法。虽然AHT与ED之间的关联已被多次探讨,但血压与ED之间的直接关联仍不明确。本综述旨在总结目前关于HT、AHT和ED之间关系的知识,特别是在年龄≥40岁的男性中。