Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
Cell Host Microbe. 2020 Dec 9;28(6):771-773. doi: 10.1016/j.chom.2020.11.006.
To colonize the nutritionally competitive environment of the gut, invading bacteria must utilize unique metabolites. Two reports in this issue of Cell Host & Microbe describe how Citrobacter rodentium and Escherichia coli leverage colonocyte derived HO to drive two distinct respiratory pathways that support their proliferation in the mouse intestine.
为了在肠道这种营养竞争激烈的环境中定殖，入侵细菌必须利用独特的代谢产物。本期《Cell Host & Microbe》中有两篇报道描述了肠杆菌科柠檬酸杆菌和大肠杆菌如何利用肠细胞衍生的 H2O2 来驱动两种不同的呼吸途径，从而支持它们在小鼠肠道内的增殖。
