Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, Zuckerberg San Francisco General Hospital, University of California, San Francisco, 1001 Potrero Avenue, Building 30, Room 3400, San Francisco, CA 94110, USA.
Infect Dis Clin North Am. 2021 Mar;35(1):169-181. doi: 10.1016/j.idc.2020.10.006. Epub 2020 Dec 7.
Persons who inject drugs are at high risk for skin and soft tissue infections. Infections range from simple abscesses and uncomplicated cellulitis to life-threatening and limb-threatening infections. These infections are predominantly caused by gram-positive organisms with Staphylococcus aureus, Streptococcus pyogenes, and other streptococcal species being most common. Although antimicrobial therapy has an important role in treatment of these infections, surgical incision, drainage, and debridement of devitalized tissue are primary. Strategies that decrease the frequency of injection drug use, needle sharing, use of contaminated equipment, and other risk behaviors may be effective in preventing these infections in persons who inject drugs.
注射毒品的人有患皮肤和软组织感染的高风险。感染的范围从简单的脓肿和单纯性蜂窝织炎到危及生命和肢体的感染。这些感染主要由革兰氏阳性菌引起，最常见的是金黄色葡萄球菌、化脓性链球菌和其他链球菌。虽然抗菌治疗在这些感染的治疗中起着重要作用，但手术切开、引流和清除坏死组织是主要的。减少注射毒品使用频率、共用针头、使用污染设备和其他危险行为的策略可能对预防注射毒品者的这些感染有效。
