Poli Philippe Amubuomombe, Orang'o Elkanah Omenge, Mwangi Ann, Barasa Felix Ayub
Department of Reproductive Health, Moi University School of Medicine Eldoret, Kenya.
Department of Behavioural Sciences, Moi University School of Medicine Eldoret, Kenya.
Eur Cardiol. 2020 Nov 13;15:e68. doi: 10.15420/ecr.2020.04. eCollection 2020 Feb.
Cardiac disease is an important life-threatening complication during pregnancy. It is frequently seen in pregnant women living in resource-limited areas and often results in premature death. The aim of this hospital-based longitudinal study was to identify factors related to adverse maternal and neonatal outcomes in pregnant women with cardiac disease in low-resource settings. The study enrolled 91 pregnant women with congenital or acquired cardiac disease over a period of 2 years in Kenya. Maternal and early neonatal deaths occurred in 12.2% and 12.6% of cases, respectively. The risk of adverse outcomes was significantly increased in those with pulmonary oedema (OR 11, 95% CI [2.3.52]; p=0.002) and arrhythmias (OR 16.9, 95% CI [2.5.113]; p=0.004). Limited access to care was significantly associated with adverse maternal outcomes (p≤0.001). Many factors contribute to adverse maternal and neonatal outcomes in pregnant women with cardiac disease. Access to comprehensive specialised care may help reduce cardiac-related complications during pregnancy.
心脏病是孕期一种重要的危及生命的并发症。在资源有限地区的孕妇中很常见，且常常导致过早死亡。这项基于医院的纵向研究旨在确定资源匮乏地区患有心脏病的孕妇中与不良孕产妇和新生儿结局相关的因素。该研究在肯尼亚历时2年招募了91名患有先天性或后天性心脏病的孕妇。孕产妇死亡和早期新生儿死亡分别发生在12.2%和12.6%的病例中。肺水肿患者（比值比11，95%置信区间[2.3,52]；p=0.002）和心律失常患者（比值比16.9，95%置信区间[2.5,113]；p=0.004）出现不良结局的风险显著增加。获得医疗服务的机会有限与不良孕产妇结局显著相关（p≤0.001）。许多因素导致患有心脏病的孕妇出现不良孕产妇和新生儿结局。获得全面专业的医疗服务可能有助于减少孕期与心脏相关的并发症。
