Ayati Mohsen, Farzin Amirreza, Rezazadeh Shahin, Ohadian Moghadam Solmaz, Amini Erfan, Behnamfar Amir
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Urol Case Rep. 2020 Nov 27;34:101510. doi: 10.1016/j.eucr.2020.101510. eCollection 2021 Jan.
Ewing sarcoma (ES) is an entity which belongs to a spectrum of neoplastic diseases called the Ewing sarcoma family of tumors (EFT). EFTs of the kidney represent less than 1% of all renal tumors. Herein, we presented a case of primary renal ES with tumor thrombosis up to vena cava who underwent radical nephrectomy and IVC tumor thrombectomy followed by adjuvant chemotherapy. Histopathology showed that the tumor composed of small uniform, dark, round cells arranged in sheets, and rosettoid pattern. The diagnosis of ESFT was confirmed by detecting EWS/FLI-1 fusion gene using reverse transcription polymerase chain reaction (RT-PCR).
尤因肉瘤（ES）是一种属于被称为尤因肉瘤家族肿瘤（EFT）的一系列肿瘤性疾病的实体。肾脏的EFT占所有肾肿瘤的比例不到1%。在此，我们报告了一例原发性肾ES伴肿瘤血栓形成至腔静脉的病例，该患者接受了根治性肾切除术和下腔静脉肿瘤血栓切除术，随后进行了辅助化疗。组织病理学显示，肿瘤由排列成片和玫瑰花结样的小而均匀、深色、圆形细胞组成。通过逆转录聚合酶链反应（RT-PCR）检测EWS/FLI-1融合基因，确诊为ESFT。
