De França Eduardo Eriko Tenório, Junior Ubirace Elihimas, Schwingel Paulo Adriano, Carvalho Celso R F, Brasileiro-Santos Maria do Socorro
Department of Physiotherapy and Postgraduate Program in Physiotherapy, Federal University of Paraiba, João Pessoa.
Postgraduate Program in Health Sciences, University of Pernambuco, Pernambuco.
Monaldi Arch Chest Dis. 2020 Dec 3;90(4). doi: 10.4081/monaldi.2020.1523.
The novel coronavirus (SARS-CoV-2) has distinct clinical manifestations that can vary from an asymptomatic condition to severe acute respiratory failure. Phenotypes are attributable to different pathophysiological mechanisms and require different treatment strategies. The assessment and identification of different phenotypes can guide therapy configurations such as oxygen therapy, non-invasive ventilation, airway management, and tracheal intubation. Further studies are essential to provide information on the influence of phenotypes in the decision of rehabilitation strategies. The sequelae left in the respiratory system of COVID-19 survivors and its limitations will be a challenge for rehabilitation services worldwide. Lung injuries are directly related to the phenotypes presented, and depending on the degree of these injuries, rehabilitation strategies can be targeted. We believe that differentiating patients, according to their respective phenotypes, can improve decision-making in treatment and individualized rehabilitation.
新型冠状病毒（SARS-CoV-2）具有不同的临床表现，从无症状状态到严重急性呼吸衰竭不等。这些表型归因于不同的病理生理机制，需要不同的治疗策略。对不同表型的评估和识别可以指导治疗方案的制定，如氧疗、无创通气、气道管理和气管插管。进一步的研究对于提供表型在康复策略决策中的影响信息至关重要。新冠病毒肺炎幸存者呼吸系统留下的后遗症及其局限性将是全球康复服务面临的一项挑战。肺损伤与所呈现的表型直接相关，根据这些损伤的程度，可以制定针对性的康复策略。我们认为，根据患者各自的表型进行区分，可以改善治疗决策和个体化康复。
