丙吡胺诱发的低血糖症及血清胰岛素升高。
Disopyramide-induced hypoglycaemia and increased serum insulin.
作者信息
Croxson M S, Shaw D W, Henley P G, Gabriel H D
机构信息
Department of Endocrinology, Auckland Hospital.
出版信息
N Z Med J. 1987 Jul 8;100(827):407-8.
PMID:3330586
Abstract
A patient treated with disopyramide presented with hypoglycaemia, a raised serum insulin level and died of pneumonia. From these findings and a review of 10 case reports, we propose that disopyramide causes hypoglycaemia by stimulation of insulin release as described for the antimalarial drugs quinine and quinidine.
摘要
一名接受丙吡胺治疗的患者出现低血糖、血清胰岛素水平升高，并死于肺炎。基于这些发现以及对10例病例报告的回顾，我们提出，丙吡胺如同抗疟药物奎宁和奎尼丁一样，通过刺激胰岛素释放导致低血糖。
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