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[计算机断层扫描在退行性共济失调研究中的应用]

[Computerized tomography in the study of degenerative ataxia].

作者信息

De Michele G, Filla A, Mansi E, Delehaye L, Cirillo S, Di Geronimo G, Geri G, Campanella G

机构信息

Clinica Neurologica I e II, Facoltà di Medicina II, Napoli.

出版信息

Riv Neurol. 1987 Nov-Dec;57(6):323-7.

PMID:3330622
Abstract

We describe the computerized tomography findings in 85 patients affected with degenerative ataxias. Cerebellar atrophy was moderate in patients with Friedreich's disease (no. 28) and early onset cerebellar ataxia with retained reflexes (no. 10) and, in Friedreich's disease, it was mostly a late feature. On the contrary, in symptomatic patients with adult onset dominant cerebellar ataxia (no. 24), cerebellar atrophy was always present and often marked. However, it was absent in 3 asymptomatic affected relatives. Infratentorial and supratentorial atrophy were frequent findings in idiopathic late onset cerebellar ataxia (no. 16).

摘要

我们描述了85例退行性共济失调患者的计算机断层扫描结果。弗里德赖希共济失调患者(28例)和早发性小脑共济失调伴反射保留患者(10例)的小脑萎缩程度为中度,在弗里德赖希共济失调患者中,这大多是晚期特征。相反,在成年发病的显性小脑共济失调症状性患者(24例)中,小脑萎缩总是存在且常常很明显。然而,3例无症状的患病亲属未出现小脑萎缩。幕下和幕上萎缩是特发性晚发性小脑共济失调(16例)的常见表现。

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