Dental Sciences Research Center, Department of Maxillofacial Radiology, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
Orthod Craniofac Res. 2021 Aug;24(3):405-413. doi: 10.1111/ocr.12455. Epub 2020 Dec 21.
To assess the fusion patterns of the spheno-occipital synchondrosis (SOS) in the age range of 9-22 using CT and CBCT images of an Iranian population.
SETTING/SAMPLE POPULATION: Spiral CT and CBCT scans of 763 subjects (459 males and 304 females) aged 9-22 were evaluated. The scans had to cover the cranial base area, and those with diseases affecting the bone density, cranial base masses and history of trauma were excluded.
Two oral and maxillofacial radiologists scored the images with regard to the status of SOS fusion based on a 5-stage system. Mann-Whitney, Kruskal-Wallis and Fisher's exact tests were used for data analysis. Age and SOS fusion stages were evaluated through Spearman correlation and linear regression methods (α = 0.01).
The earliest age for onset of SOS fusion was 9 in both sexes. Open SOS could be observed until the age of 15 and 14 in males and females, respectively. The earliest age of complete fusion was 12 in males and 13 in females. Furthermore, there was a significant, positive correlation between age and the different stages of SOS fusion (P < .001).
A significant correlation exists between age and the fusion stages of SOS, rendering it an appropriate means of age estimation during growth periods. Fusion of SOS begins approximately 2 years earlier in females; however, it ends at the age of 17 in both sexes. The fusion scar can be detected up to the age of 12 and 13 in males and females, respectively.
利用伊朗人群的 CT 和 CBCT 图像评估 9-22 岁人群蝶枕结合部（SOS）的融合模式。
设置/样本人群：评估了 763 名 9-22 岁受试者（459 名男性和 304 名女性）的螺旋 CT 和 CBCT 扫描。扫描必须覆盖颅底区域，排除那些患有影响骨密度、颅底肿块和创伤史的疾病的患者。
两位口腔颌面放射科医生根据 5 级系统对 SOS 融合状态的图像进行评分。使用 Mann-Whitney、Kruskal-Wallis 和 Fisher 精确检验进行数据分析。年龄和 SOS 融合阶段通过 Spearman 相关和线性回归方法进行评估（α=0.01）。
SOS 融合的最早年龄在两性均为 9 岁。开放性 SOS 可分别在男性和女性观察到 15 岁和 14 岁。完全融合的最早年龄为男性 12 岁，女性 13 岁。此外，年龄与 SOS 融合的不同阶段之间存在显著的正相关关系（P<0.001）。
年龄与 SOS 融合阶段之间存在显著相关性，这使其成为生长期间年龄估计的合适方法。SOS 的融合在女性中大约早开始 2 年；然而，两性均在 17 岁结束。融合瘢痕在男性和女性中分别可检测到 12 岁和 13 岁。
