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南美洲五国的流感疫苗犹豫。信心、自满和便利是免疫率的决定因素。

Influenza vaccination hesitancy in five countries of South America. Confidence, complacency and convenience as determinants of immunization rates.

机构信息

Universidad Anáhuac, Mexico City, Mexico.

Instituto Nacional de Salud Pública, Cuernavaca, Mexico.

出版信息

PLoS One. 2020 Dec 11;15(12):e0243833. doi: 10.1371/journal.pone.0243833. eCollection 2020.

Abstract

INTRODUCTION

Influenza morbidity and mortality are significant in the countries of South America, yet influenza vaccination is as low as 56.7% among pregnant women, reaching 76.7% of adults with chronic diseases. This article measures the relative values for the vaccination hesitancy indicators of confidence, complacency and convenience by risk-groups in urban areas of five countries of South America with contrasting vaccination rates, analyzing their association with sociodemographic variables and self-reported immunization status.

METHODS

An exit survey was applied to 640 individuals per country in Brazil, Chile, Paraguay, Peru and Uruguay, distributed equally across risk groups of older adults, adults with risk factors, children ≤6 and pregnant women. Indicators were constructed for vaccine confidence, complacency and convenience. Analysis of variance and multiple logistic analysis was undertaken.

RESULTS

Adults with risk factors are somewhat more confident of the influenza vaccine yet also more complacent. Convenience is higher for mothers of minors. Children and older adults report higher levels of vaccination. The 3Cs are more different across countries than across risk groups, with values for Chile higher for confidence and those for Uruguay the lowest. Complacency is lower in Brazil and higher in Uruguay. Results suggest that confidence and complacency affect vaccination rates across risk groups and countries.

CONCLUSIONS

Influenza vaccine confidence, complacency and convenience have to be bolstered to improve effective coverage across all risk groups in the urban areas of the countries studied. The role played by country contextual and national vaccination programs has to be further researched in relation to effective coverage of influenza vaccine.

摘要

简介

在南美洲国家,流感发病率和死亡率很高,但孕妇的流感疫苗接种率低至 56.7%,慢性病患者的接种率为 76.7%。本文通过对五个具有不同疫苗接种率的南美国家城市地区的不同风险群体的疫苗犹豫指标(信心、自满和便利性)进行衡量,分析其与社会人口统计学变量和自我报告免疫状况的关系。

方法

在巴西、智利、巴拉圭、秘鲁和乌拉圭,每个国家对 640 名个体进行了一项出口调查,这些个体在老年人、有危险因素的成年人、≤6 岁的儿童和孕妇等风险群体中平均分配。为疫苗信心、自满和便利性构建了指标。进行方差分析和多逻辑回归分析。

结果

有危险因素的成年人对流感疫苗更有信心,但也更自满。未成年人的母亲更方便接种疫苗。儿童和老年人报告的接种率更高。3C 在国家之间的差异大于风险群体之间的差异,智利的信心值较高,乌拉圭的信心值较低。巴西的自满程度较低,乌拉圭的自满程度较高。结果表明,信心和自满情绪会影响所有风险群体的疫苗接种率,无论在国家还是风险群体。

结论

为了提高研究国家城市地区所有风险群体的有效疫苗接种率,必须增强流感疫苗的信心、自满和便利性。必须进一步研究国家背景和国家疫苗接种计划在流感疫苗有效接种率方面的作用。

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