Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.
Department of Subspecialty General Surgery, Mayo Clinic, Rochester, MN 55905, USA.
Eat Behav. 2021 Jan;40:101462. doi: 10.1016/j.eatbeh.2020.101462. Epub 2020 Nov 22.
Bipolar disorder (BP) is highly comorbid with obesity, however, little is known about how BP might be associated with bariatric surgery outcomes.
In this retrospective clinical cohort study, 1034 patients completed a psychological evaluation, and screening positive for possible BP was defined as a score ≥7 and moderate disability on the Mood Disorders Questionnaire. Food addiction (FA), subthreshold binge eating disorder (BED), and illegal drug use were also assessed using standardized questionnaires.
The 54 (5.2%) patients screening positive for BP were less likely to have bariatric surgery compared to 980 (94.8%) patients who screened negative for BP (5 patients or 9.3% vs 273 patients, or 27.9%). Patients with possible BP also had significantly higher prevalence of FA (37% vs 13.2%), subthreshold BED (29.6% vs 8.3%) and illegal drug use (7.4% vs 2.1%).
In this retrospective clinical cohort study, patients who screened positive for BP had a higher prevalence of food addiction, subthreshold binge eating disorder and recent illegal drug use. They also demonstrated lower completion rates for having bariatric surgery. Clearly, more needs to be learned about how to help patients with symptoms of bipolar disorder manage their obesity and behavioral challenges.
双相情感障碍（BP）与肥胖高度共病，但对于 BP 如何与减重手术结果相关知之甚少。
在这项回顾性临床队列研究中，1034 名患者完成了心理评估，对心境障碍问卷评分≥7 分且中度残疾的患者筛查为可能存在 BP。还使用标准化问卷评估了食物成瘾（FA）、阈下暴食障碍（BED）和非法药物使用。
与 980 名筛查 BP 阴性的患者（5 名患者或 9.3%与 273 名患者，或 27.9%）相比，筛查阳性可能患有 BP 的 54 名患者（5.2%）进行减重手术的可能性较低。可能患有 BP 的患者也有更高的 FA（37%比 13.2%）、阈下 BED（29.6%比 8.3%）和最近非法药物使用（7.4%比 2.1%）的发生率。
在这项回顾性临床队列研究中，筛查 BP 阳性的患者有更高的食物成瘾、阈下暴食障碍和最近非法药物使用的发生率。他们也表现出更低的减重手术完成率。显然，需要进一步了解如何帮助有双相情感障碍症状的患者管理他们的肥胖和行为挑战。
