Katzir Miki, Rustagi Tarush, Hatef Jeffrey, Mendel Ehud
Department of Neurological Surgery, 12306Ohio State University Wexner Medical Center, The James Cancer Hospital & Solove Research Institute, Columbus, OH, USA.
Department of Spine Surgery, Indian Spinal Injuries Centre, New Delhi, India.
Global Spine J. 2022 Jun;12(5):858-865. doi: 10.1177/2192568220975375. Epub 2020 Dec 14.
Retrospective case series.
Patient with metastatic cancer frequently require spinal operations for neural decompression and stabilization, most commonly thoracic vertebrectomy with reconstruction. Objective of the study was to assess economic aspects associated with use of cement versus expandable cage in patients with single level thoracic metastatic disease. We also looked at the differences in the clinical, radiological, complications and survival differences to assess non-inferiority of PMMA over cages.
The electronic medical records of patients undergoing single level thoracic vertebrectomy and reconstruction were reviewed. Two groups were made: PMMA and EC. Totals surgical cost, implant costs was analyzed. We also looked at the clinical/ radiological outcome, complication and survival analysis.
96 patients were identified including 70 one-level resections. For 1-level surgeries, Implant costs for use of cement-$75 compared to $9000 for cages. Overall surgical cost was significantly less for PMMA compared to use of EC. No difference was seen in clinical outcome or complication was seen. We noticed significantly better kyphosis correction in the PMMA group.
Polymethylmethacrylate cement offers significant cost advantage for reconstruction after thoracic vertebrectomy. It also allows for better kyphosis correction and comparable clinical outcomes and non-inferior to cages.
回顾性病例系列。
转移性癌症患者常需进行脊柱手术以实现神经减压和稳定,最常见的是胸椎切除术并重建。本研究的目的是评估在单节段胸椎转移性疾病患者中使用骨水泥与可扩张椎间融合器的经济相关方面。我们还研究了临床、放射学、并发症及生存方面的差异,以评估聚甲基丙烯酸甲酯(PMMA)相对于椎间融合器的非劣效性。
回顾接受单节段胸椎切除术并重建患者的电子病历。分为两组:PMMA组和椎间融合器(EC)组。分析了总手术成本、植入物成本。我们还进行了临床/放射学结果、并发症及生存分析。
共确定96例患者,其中包括70例单节段切除术。对于单节段手术,使用骨水泥的植入物成本为75美元,而使用椎间融合器的成本为9000美元。与使用椎间融合器相比,PMMA的总体手术成本显著更低。临床结果或并发症方面未见差异。我们注意到PMMA组的后凸畸形矫正明显更好。
聚甲基丙烯酸甲酯骨水泥在胸椎切除术后重建方面具有显著的成本优势。它还能实现更好的后凸畸形矫正,临床结果相当,且不劣于椎间融合器。