Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Expert Rev Anti Infect Ther. 2021 Aug;19(8):1047-1051. doi: 10.1080/14787210.2021.1863789. Epub 2020 Dec 21.
To quantify antimicrobial use in inpatients setting as part of antimicrobial stewardship program surveillance.
Antimicrobial use was obtained using a pre-designed data collection form in this point prevalence study. Setting: The study was conducted in a tertiary academic hospital in the North of Jordan on 13 August 2018. Main outcome measures: antimicrobial use was determined using two methods: defined daily use (DDD) and days of therapy (DOT).
This study identified antimicrobial use in 144 patients. Carbapenems, glycopeptides, and piperacillin-tazobactam were the most utilized antimicrobials in the inpatients' setting in both measures DDD and DOT. The highest prescription rate of antibiotics was in the internal medicine wards (49.8 DDD/100 admissions), followed by surgery wards (33.2 DDD/100 admissions) and intensive care unit (20.6 DDD/100 admissions).
This surveillance study addressed patterns of antimicrobial usage in inpatients settings in a tertiary care hospital in Jordan. This practice is feasible and could be adopted routinely by antimicrobial stewardship programs.
作为抗菌药物管理计划监测的一部分,量化住院患者环境中的抗菌药物使用情况。
在这项现况研究中,使用预先设计的数据收集表获取抗菌药物使用情况。
该研究于 2018 年 8 月 13 日在约旦北部的一家三级学术医院进行。
使用两种方法确定抗菌药物使用情况:限定日剂量(DDD)和治疗日数(DOT)。
本研究在 144 名患者中发现了抗菌药物的使用。碳青霉烯类、糖肽类和哌拉西林他唑巴坦在 DDD 和 DOT 两种测量方法中均为住院患者环境中使用最多的抗菌药物。抗生素的最高处方率出现在内科病房(49.8 DDD/100 人次),其次是外科病房(33.2 DDD/100 人次)和重症监护病房(20.6 DDD/100 人次)。
这项监测研究针对约旦一家三级护理医院住院患者环境中的抗菌药物使用模式进行了研究。这种做法是可行的,可以被抗菌药物管理计划常规采用。