Davis Korbin M, Ryan Joshua L, Aaron Vasantha D, Sims Justin B
Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indianapolis, IN.
Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indianapolis, IN.
Semin Ultrasound CT MR. 2020 Dec;41(6):521-529. doi: 10.1053/j.sult.2020.08.006. Epub 2020 Aug 29.
Advances in nuclear medicine have revolutionized our ability to accurately diagnose patients with a wide array of neurologic pathologies and provide appropriate therapy. The development of new radiopharmaceuticals has made possible the identification of regional differences in brain tissue composition and metabolism. In addition, the evolution of 3-dimensional molecular imaging followed by fusion with computed tomography and magnetic resonance imaging have allowed for more precise localization of pathologies. This review will introduce single photon emission computed tomography and positron emission tomographic imaging of the brain, including the history of their development, technical considerations, and a brief overview of pertinent radiopharmaceuticals and their applications.
核医学的进展彻底改变了我们准确诊断患有各种神经病理学疾病患者并提供适当治疗的能力。新型放射性药物的开发使识别脑组织成分和代谢的区域差异成为可能。此外，三维分子成像技术的发展，随后与计算机断层扫描和磁共振成像融合，使得病变的定位更加精确。本综述将介绍脑的单光子发射计算机断层扫描和正电子发射断层扫描成像，包括其发展历程、技术要点，以及相关放射性药物及其应用的简要概述。
