Department of Radiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE..
Department of Radiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE.
Semin Ultrasound CT MR. 2020 Dec;41(6):562-571. doi: 10.1053/j.sult.2020.08.010. Epub 2020 Aug 29.
Dementia syndromes present a diagnostic challenge given their overlapping clinical features and insidious presentations. Cerebral 2-deoxy-2-[F-18]fluoroglucose (FDG) positron emission tomography (PET) is a functional imaging modality commonly used in the evaluation of dementia. While its role in the clinical assessment of dementia is evolving, FDG PET allows for qualitative and quantitative characterization of major dementia syndromes and variants by means of detecting distinct patterns of cortical hypometabolism. Familiarity with these "metabolic signatures" in dementia syndromes can be helpful when interpreting cerebral FDG PET.
由于痴呆综合征具有重叠的临床特征和隐匿性表现，因此诊断具有挑战性。脑 2-脱氧-2-[F-18]氟葡萄糖（FDG）正电子发射断层扫描（PET）是一种常用于评估痴呆的功能成像方式。虽然它在痴呆的临床评估中的作用仍在不断发展，但 FDG PET 通过检测皮质代谢低下的不同模式，允许对主要痴呆综合征和变体进行定性和定量描述。当解释脑 FDG PET 时，熟悉痴呆综合征中的这些“代谢特征”可能会有所帮助。
