Hammer Karissa C, Pavlovic Zoran J, Raff Marika R, Bradley Danielle E, Cobb Christina N, Elliot Stephanie E, Fogg Louis L, Hirshfeld-Cytron Jennifer E
Department of Obstetrics and Gynecology, Rush University Medical Center, Chicago, USA.
Ovia Health, Boston, IL, USA.
J Hum Reprod Sci. 2020 Jul-Sep;13(3):221-234. doi: 10.4103/jhrs.JHRS_173_19. Epub 2020 Oct 27.
There is limited understanding about parent perspectives of newborn development after assisted reproductive technology (ART). The use of ART is known to increase the risk of premature delivery and low birth weight. Both of these factors are associated with developmental delay. To our knowledge, no study has investigated how parents perceive their child's development after use of ART.
To investigate how the parent perspective of childhood development after ART use compares to the parent perspective of spontaneously conceived children.
This is a digital survey collecting data on parent perspective of newborn development after ART and spontaneous conception.
Invitation to participate was sent via E-mail to users of a () mobile parenting application (). Surveys were collected from August 30, 2018, to September 12, 2018, and a total of 1881 surveys were collected.
Analysis was performed with Chi-square cross-tabulations and ANOVA.
Overall, 13,600 (12%) of users who were delivered the E-mail engaged with the content. Of those users, 2739 (20%) initiated the survey and 1881 (69%) completed the survey and were included in the analyses. When comparing spontaneous conception to ART, parents reported similar developmental milestones at most ages. A significant difference existed at 12 months where those who had used ART were more likely to report their child met all milestones. This difference did not persist for subsequent ages.
From the parent perspective, children conceived using ART methods should be expected to meet the same age-based developmental milestones as their spontaneously conceived peers.
对于辅助生殖技术（ART）后父母对新生儿发育的看法，人们了解有限。已知使用ART会增加早产和低出生体重的风险。这两个因素都与发育迟缓有关。据我们所知，尚无研究调查父母在使用ART后如何看待孩子的发育情况。
调查使用ART后父母对儿童发育的看法与自然受孕儿童的父母看法相比如何。
这是一项数字调查，收集关于ART和自然受孕后父母对新生儿发育看法的数据。
通过电子邮件向一款（）移动育儿应用程序的用户发送参与邀请。调查于2018年8月30日至2018年9月12日收集，共收集到1881份调查问卷。
采用卡方交叉表和方差分析进行分析。
总体而言，收到电子邮件的用户中有13,600人（12%）参与了相关内容。在这些用户中，2739人（20%）开始了调查，1881人（69%）完成了调查并被纳入分析。将自然受孕与ART受孕进行比较时，父母报告在大多数年龄段儿童的发育里程碑相似。在12个月时存在显著差异，使用ART受孕的父母更有可能报告他们的孩子达到了所有里程碑。这种差异在随后的年龄段中没有持续存在。
从父母的角度来看，使用ART方法受孕的儿童应该有望与自然受孕的同龄人达到相同的基于年龄的发育里程碑。
