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鼻中隔成形术后嗅觉功能的变化。一项系统评价与荟萃分析。

Change in olfactory function after septoplasty. A systematic review and meta-analysis.

作者信息

Grabosky A, Mackers P, Langdon C, Alobid I

机构信息

Medical Graduate, University of Barcelona, Barcelona, Spain.

Department of Otorhinolaryngology, Hospital del Mar, Barcelona, Spain.

出版信息

Rhinology. 2021 Apr 1;59(2):144-150. doi: 10.4193/Rhin20.252.

DOI:10.4193/Rhin20.252
PMID:33320116
Abstract

BACKGROUND

Septoplasty is one of the most frequently performed surgeries. However, there remains a question as to the effect of such intervention on the sense of smell. This study aims to examine the available evidence regarding the effect of septoplasty on the sense of smell.

METHODS

A database search was performed using PubMed, ScienceDirect, Google Scholar and The Cochrane Library databases from January 1990 to February 2020. Search terms included smell, olfaction, odor, septum, septoplasty, and septorhinoplasty. A meta-analysis was performed with 12 studies that provided sufficient data on change in olfaction.

RESULTS

14 studies met the inclusion criteria, and 2 additional studies were included manually; comprising a total of 996 patients and 25 controls. Significant improvement in olfactory test scores was observed in all tests. Pre- and postoperative differences in means were 0.63 for BSIT, 0.80 for CCCRC test, 1.16 for odor threshold, 1.43 for odor discrimination, and 1.18 for odor identification.

CONCLUSIONS

Septoplasty seems to improve olfactory function. However, the outcome of this intervention is discrete and not equal for all patients, so further randomized trials are needed to confirm current findings.

摘要

背景

鼻中隔成形术是最常开展的手术之一。然而,这种干预对嗅觉的影响仍存在疑问。本研究旨在审视关于鼻中隔成形术对嗅觉影响的现有证据。

方法

于1990年1月至2020年2月期间,使用PubMed、ScienceDirect、谷歌学术和考克兰图书馆数据库进行数据库检索。检索词包括嗅觉、嗅觉功能、气味、鼻中隔、鼻中隔成形术和鼻 septorhinoplasty。对12项提供了嗅觉变化充分数据的研究进行荟萃分析。

结果

14项研究符合纳入标准,另外手动纳入2项研究;共计996例患者和25例对照。在所有测试中均观察到嗅觉测试分数有显著改善。术前和术后平均差异在嗅棒嗅觉识别测试(BSIT)中为0.63,在康奈尔嗅觉识别测试(CCCRC)中为0.80,在气味阈值中为1.16,在气味辨别中为1.43,在气味识别中为1.18。

结论

鼻中隔成形术似乎能改善嗅觉功能。然而,这种干预的结果是离散的,并非对所有患者都相同,因此需要进一步的随机试验来证实当前的研究结果。

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