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在模拟、计量和临床病例中,比较数字乳腺断层合成中使用的管电压的光谱和平均腺体剂量。

COMPARISON OF SPECTRA AND MEAN GLANDULAR DOSE WITH TUBE VOLTAGES USED IN DIGITAL BREAST TOMOSYNTHESIS FROM SIMULATED, METROLOGICAL AND CLINICAL CASES.

机构信息

COPPE - Rio de Janeiro Federal University, Av. Horácio Macedo, 2030, Bloco G, Cidade Universitária, Ilha do Fundão, CEP 221941-914, Rio de Janeiro, Brazil.

Radiologic Sciences Laboratory - Rio de Janeiro State University, Rua São Francisco Xavier, Room136, 524, PHLC, CEP 20550-900, Rio de Janeiro, Brazil.

出版信息

Radiat Prot Dosimetry. 2020 Dec 30;192(3):402-412. doi: 10.1093/rpd/ncaa198.

DOI:10.1093/rpd/ncaa198
PMID:33320943
Abstract

Digital breast tomosynthesis (DBT) is a screening and diagnostic modality that acquires images of a breast at multiple angles during a short scan. The Selenia Dimensions (Hologic, Bedford, Mass) DBT system can perform both full-field digital mammography and DBT. The system acquires 25 projections over a 15° angular range (from -7.5° to +7.5°). X-ray spectroscopy is generally linked with a high-resolution semiconductor detector through a correction to its energy response function. The energy spectrum describes the radiation field, in which several quality parameters can be extracted, such as the effective energy, half-value layer and exposure. X-ray spectroscopy is usually performed with solid-state semiconductor detectors. Radiation dose is a concern in mammography, as the current protocols recommend that medical physicians evaluate mean glandular dose (MGD) as a part of service quality control. Studies are needed for radiation dose optimization from tomosynthesis patients. The COMET metrological X-ray tube, considered as with a constant potential and cooled, has proved to be a crucial tool in order to obtain the high energy resolution for low-energy radiographs in mammography. The Monte Carlo method, through Monte Carlo N-Particle eXtended (MCNPX), was proven to be an essential tool for image formation and posterior analysis of the deposited dose from breast simulators and radiographic contrast evaluation, for several anode/filter combinations. The purpose of this work was to assess the MGD and spectra in slabs of polymethyl methacrylate (PMMA) and breast equivalent thicknesses using four experiments with a Hologic Selenia Dimensions mammography X-ray tube with multimeter, a spectrometer (only for spectra, in this case), a metrological X-ray tube with a multimeter, and the MCNPX code. References indicate that the real conditions for a mammography X-ray tube that conducts tomosynthesis include tube voltages of 26, 29, 30 and 33 kVp. Taking into account several thicknesses of PMMA, both the MGD and spectral results were in accordance with the references. Most of the spectra were in accordance with the references, showing that the resources used in the experiments can evaluate the energy level received by a patient. The MGD values were lower than those in the references from 30 to 50 mm PMMA, and the data can be used for improvements in the detectors used in the Laboratory of Metrology in the State of Rio de Janeiro University, Brazil. Additionally, in the future, optimization of image quality can be performed for both semiconductors and mammography X-ray equipment.

摘要

数字乳腺断层合成(DBT)是一种在短时间内获取乳房多个角度图像的筛查和诊断方式。Selenia Dimensions(Hologic,马萨诸塞州贝德福德)DBT 系统可以同时进行全数字乳腺摄影和 DBT。该系统在 15°角度范围内采集 25 个投影(从-7.5°到+7.5°)。X 射线光谱学通常通过对其能量响应函数进行校正来与高分辨率半导体探测器相关联。能谱描述了辐射场,从中可以提取出几个质量参数,如有效能量、半价层和曝光量。X 射线光谱学通常使用固态半导体探测器进行。在乳腺摄影中,辐射剂量是一个关注点,因为目前的协议建议医疗医师将腺体剂量(MGD)评估作为服务质量控制的一部分。需要进行研究以优化断层合成患者的辐射剂量。COMET 计量 X 射线管被认为是具有恒定电位和冷却的,已被证明是获得乳腺摄影中低能射线高能量分辨率的关键工具。蒙特卡罗方法通过蒙特卡罗 N 粒子扩展(MCNPX)被证明是用于形成图像和分析乳房模拟器中沉积剂量以及评估射线照相对比度的后处理的重要工具,适用于多种阳极/滤光片组合。这项工作的目的是使用 Hologic Selenia Dimensions 乳腺摄影 X 射线管与多用途表、光谱仪(仅用于光谱,在这种情况下)、带有多用途表的计量 X 射线管和 MCNPX 代码进行的四个实验,评估聚甲基丙烯酸甲酯(PMMA)和乳腺等效厚度平板中的 MGD 和光谱。参考文献表明,进行断层合成的乳腺 X 射线管的实际条件包括 26、29、30 和 33 kVp 的管电压。考虑到 PMMA 的多个厚度,MGD 和光谱结果都与参考文献一致。大多数光谱与参考文献一致,表明实验中使用的资源可以评估患者接收到的能量水平。MGD 值在 30 至 50 毫米 PMMA 之间低于参考文献值,并且数据可用于改进巴西里约热内卢联邦大学计量学实验室中使用的探测器。此外,未来可以对半导体和乳腺 X 射线设备的图像质量进行优化。

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