衣原体对宿主激酶的劫持与利用
Hijacking and Use of Host Kinases by Chlamydiae.
作者信息
Sah Prakash, Lutter Erika I
机构信息
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK 74078, USA.
出版信息
Pathogens. 2020 Dec 10;9(12):1034. doi: 10.3390/pathogens9121034.
species are causative agents of sexually transmitted infections, blinding trachoma, and animal infections with zoonotic potential. Being an obligate intracellular pathogen, relies on the host cell for its survival and development, subverting various host cell processes throughout the infection cycle. A key subset of host proteins utilized by include an assortment of host kinase signaling networks which are vital for many chlamydial processes including entry, nutrient acquisition, and suppression of host cell apoptosis. In this review, we summarize the recent advancements in our understanding of host kinase subversion by .
衣原体属物种是性传播感染、致盲性沙眼以及具有人畜共患病潜力的动物感染的病原体。作为一种专性细胞内病原体,衣原体依赖宿主细胞生存和发育,在整个感染周期中破坏各种宿主细胞过程。衣原体利用的宿主蛋白的一个关键子集包括各种宿主激酶信号网络,这些网络对衣原体的许多过程至关重要,包括进入宿主细胞、获取营养以及抑制宿主细胞凋亡。在这篇综述中,我们总结了我们对衣原体颠覆宿主激酶机制理解的最新进展。
相似文献
Pathogens. 2020-12-10
Front Microbiol. 2019-10-9
Microorganisms. 2019-11-22
Trends Microbiol. 2009-10
Harefuah. 2004-9
Front Cell Infect Microbiol. 2017-12-11
Microb Pathog. 2019-12-30
引用本文的文献
Front Cell Infect Microbiol. 2023
本文引用的文献
Int J Mol Sci. 2019-12-21
Pathog Dis. 2019-8-1
Front Cell Infect Microbiol. 2018-11-30
Vector Borne Zoonotic Dis. 2018-11
Front Cell Infect Microbiol. 2017-12-11