Colon E J, de Weerd A W
Department of Clinical Neurophysiology, St. Radboud Hospital, Nijmegen, The Netherlands.
J Clin Neurophysiol. 1986 Oct;3(4):279-96. doi: 10.1097/00004691-198610000-00001.
Theoretically, long-latency somatosensory evoked potentials (SEPs) provide information on the function of somatosensory associative cortical structures. Their potential role in clinical studies and research has been hampered by the lack of standardized methodology in the use of these SEPs. Other factors, such as drugs, simultaneous stimuli, and state of consciousness, also have far-reaching influences on the various parameters of long-latency SEPs. The knowledge of the origin of most SEP components is at best fragmentary; studies on clinical-electrophysiological correlations seem to be hopeful in this respect. As yet, clinical applications of long-latency SEPs are limited; for future research, studies of disturbances of SEPs are most promising, mainly with regard to diseases of the gray matter, the influence of drugs on the cerebral function, and psychopathology.
理论上，长潜伏期体感诱发电位（SEP）可提供有关体感联合皮质结构功能的信息。这些SEP在临床研究和科研中的潜在作用因使用方法缺乏标准化而受到阻碍。其他因素，如药物、同时出现的刺激和意识状态，也对长潜伏期SEP的各项参数有深远影响。大多数SEP成分的起源知识充其量只是支离破碎的；在这方面，临床-电生理相关性研究似乎很有前景。目前，长潜伏期SEP的临床应用有限；对于未来的研究，SEP紊乱的研究最有前景，主要涉及灰质疾病、药物对脑功能的影响以及精神病理学。
