Semble E L, Wu W C
Bowman Gray School of Medicine, Winston-Salem, North Carolina.
Am Fam Physician. 1987 Jun;35(6):101-8.
Gastric mucosal damage is a common side effect of nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs may cause gastrointestinal symptoms, gastric erosions, peptic ulcers or upper gastrointestinal bleeding. Therefore, NSAIDs should be used cautiously in patients with a history of gastrointestinal lesions. Drugs that may be useful in preventing or treating NSAID-induced gastric mucosal injury are under intensive clinical investigation.
胃黏膜损伤是非甾体抗炎药(NSAIDs)常见的副作用。这些药物可能会引起胃肠道症状、胃糜烂、消化性溃疡或上消化道出血。因此,有胃肠道病变病史的患者应谨慎使用NSAIDs。目前正在对可能有助于预防或治疗NSAIDs引起的胃黏膜损伤的药物进行深入的临床研究。