[中国昆明5至14岁儿童肺通气功能参数：基于扎普莱塔尔方程的测量值与预测值的对比分析]
[Pulmonary ventilation function parameters of children aged 5-14 years in Kunming, China: a comparative analysis of measured values versus predicted values based on Zapletal equation].
作者信息
Yang Jie, Fu Hong-Min, Bai Tao-Zhen, Wang Fan, Zhang Ou, Zhang Shu-Dong, Nie Wen-Sha
机构信息
Department of Respiratory and Critical Diseases, Children's Hospital of Kunming Medical University, Kunming 650032, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2020 Dec;22(12):1313-1319. doi: 10.7499/j.issn.1008-8830.2007185.
OBJECTIVE
To study the percentage of the measured values of the main pulmonary ventilation function parameters in their predicted values based on Zapletal equation among healthy children aged 5-14 years in Kunming, China, and to provide a basis for accurate judgment of pulmonary ventilation function in clinical practice.
METHODS
A total of 702 healthy children aged 5-14 years (352 boys and 350 girls) from Kunming were enrolled. The Jaeger spirometer was used to measure the nine indices:forced vital capacity (FVC), forced expiratory volume in one second (FEV1), ratio of forced expiratory volume in one second to forced vital capacity (FEV1/FVC), maximal mid-expiratory flow (MMEF), forced expiratory flow at 25% of forced vital capacity (FEF25), forced expiratory flow at 50% of forced vital capacity (FEF50), forced expiratory flow at 75% of forced vital capacity (FEF75), peak expiratory flow (PEF), and maximal voluntary ventilation (MVV). The values obtained from the Zapletal equation of predicted values provided by the spirometer were used as the predicted values of children, and the percentage of measured values in predicted values was calculated.
RESULTS
In the 702 children, the percentages of the measured values of the main pulmonary ventilation function parameters PEF, FVC, FEV1, FEV1/FVC, and MVV in their predicted values fluctuated from 102% to 114%, 94% to 108%, 98% to 113%, 98% to 107%, and 141% to 183% respectively. As for the main airway velocity parameters, the percentages of the measured values of FEF25, FEF50, FEF75, and MMEF in their predicted values fluctuated from 98% to 116%, 85% to 102%, 71% to 98%, and 83% to 100% respectively. The percentages of the measured values of PEF, FVC, FEV1, FEV1/FVC, MVV, FEF25, FEF50, FEF75, and MMEF in their predicted values had the lower limits of normal of 88.2%, 88.4%, 92.0%, 94.4%, 118.5%, 82.9%, 70.0%, 62.1%, and 70.1% respectively.
CONCLUSIONS
There are differences between pulmonary ventilation function parameter levels and normal values provided by Zapletal equation in healthy children aged 5-14 years in Kunming. As for the pulmonary ventilation function parameters of PEF, FVC, FEV, FEV1/FVC, MVV, FEF25, FEF50, FEF75, and MMEF in these children, the lower limits of normal of measured values in predicted values may be determined as 88.2%, 88.4%, 92.0%, 94.4%, 118.5%, 82.9%, 70.0%, 62.1%, and 70.1% respectively.
目的
研究中国昆明5-14岁健康儿童主要肺通气功能参数实测值占基于扎普莱塔尔方程预测值的百分比，为临床实践中准确判断肺通气功能提供依据。
方法
纳入昆明市702名5-14岁健康儿童（男352名，女350名）。采用耶格肺功能仪测量9项指标：用力肺活量（FVC）、一秒用力呼气容积（FEV1）、一秒用力呼气容积与用力肺活量比值（FEV1/FVC）、最大呼气中期流速（MMEF）、用力肺活量25%时的用力呼气流量（FEF25）、用力肺活量50%时的用力呼气流量（FEF50）、用力肺活量75%时的用力呼气流量（FEF75）、呼气峰值流速（PEF）和最大自主通气量（MVV）。将肺功能仪提供的基于扎普莱塔尔方程预测值作为儿童的预测值，计算实测值占预测值的百分比。
结果
702名儿童中，主要肺通气功能参数PEF、FVC、FEV1、FEV1/FVC和MVV实测值占预测值的百分比分别在102%至114%、94%至108%、98%至113%、98%至107%和141%至183%之间波动。对于主要气道流速参数，FEF25、FEF50、FEF75和MMEF实测值占预测值的百分比分别在98%至116%、85%至102%、71%至98%和83%至100%之间波动。PEF、FVC、FEV1、FEV1/FVC、MVV、FEF25、FEF50、FEF75和MMEF实测值占预测值的百分比正常下限分别为88.2%、88.4%、92.0%、94.4%、118.5%、82.9%、70.0%、62.1%和70.1%。
结论
昆明5-14岁健康儿童肺通气功能参数水平与扎普莱塔尔方程提供的正常值存在差异。对于这些儿童的肺通气功能参数PEF、FVC、FEV、FEV1/FVC、MVV、FEF25、FEF50、FEF75和MMEF，实测值占预测值的正常下限可分别确定为88.2%、88.4%、92.0%、94.4%、118.5%、82.9%、70.0%、62.1%和70.1%。
Zotero 插件