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酷似肝脏恶性肿瘤的肝脏类风湿结节:罕见病例

Liver rheumatoid nodules imitating liver malignancy: a rare occurrence.

作者信息

Wee Jason, Sobhi Salar, De Boer Bastiaan, Xu Dan

机构信息

Faculty of Health and Medical Sciences, University of Western Australia, Crawley, Western Australia, Australia.

Anatomical Pathology, PathWest Laboratory Medical WA, Murdoch, Western Australia, Australia.

出版信息

BMJ Case Rep. 2020 Dec 16;13(12):e234366. doi: 10.1136/bcr-2020-234366.

DOI:10.1136/bcr-2020-234366
PMID:33328208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7745683/
Abstract

We describe a case of a 61-year-old man with a background of rheumatoid arthritis who presented to the emergency department with a single-reported episode of haemoptysis on the background of an upper respiratory tract infection. A CT scan revealed an incidental 40 mm mass in upper right lobe of the liver abutting the diaphragmatic surface. A subsequent positron emission tomography scan confirmed the mass and raised the possibility of another lesion in the liver raising the suspicion of malignancy. The case was complicated by the inability to perform a fine needle aspiration biopsy due to the mass' proximity to the diaphragm. After discussion with the patient, it was decided to resect the affected liver segment. Histological analysis of the mass revealed localised necrotising granulomatous inflammation suggestive of a rheumatoid nodule, which is seldom reported in the literature.

摘要

我们描述了一例61岁男性患者,他有类风湿关节炎病史,因上呼吸道感染出现单次咯血后就诊于急诊科。CT扫描显示肝脏右叶上部有一个偶然发现的40毫米肿块,紧邻膈面。随后的正电子发射断层扫描证实了该肿块,并发现肝脏可能存在另一个病变,怀疑为恶性肿瘤。由于肿块靠近膈肌,无法进行细针穿刺活检,使该病例变得复杂。与患者讨论后,决定切除受影响的肝段。肿块的组织学分析显示为局限性坏死性肉芽肿性炎症,提示为类风湿结节,这在文献中鲜有报道。

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引用本文的文献

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本文引用的文献

1
Granulomas of the liver.肝脏肉芽肿。
Clin Liver Dis (Hoboken). 2016 Apr 27;7(4):92-96. doi: 10.1002/cld.544. eCollection 2016 Apr.
2
A Large Rheumatoid Nodule Mimicking Hepatic Malignancy.
Hepatology. 2019 Mar;69(3):1345-1348. doi: 10.1002/hep.30261. Epub 2019 Feb 8.
3
Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies.类风湿性关节炎:病理机制与现代药物治疗
Bone Res. 2018 Apr 27;6:15. doi: 10.1038/s41413-018-0016-9. eCollection 2018.
4
Clinical connection between rheumatoid arthritis and liver damage.类风湿关节炎与肝损伤的临床关联。
Rheumatol Int. 2018 May;38(5):715-724. doi: 10.1007/s00296-018-4021-5. Epub 2018 Apr 7.
5
Risk of liver disease in methotrexate treated patients.甲氨蝶呤治疗患者的肝脏疾病风险。
World J Hepatol. 2017 Sep 18;9(26):1092-1100. doi: 10.4254/wjh.v9.i26.1092.
6
Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis: A network meta-analysis.甲氨蝶呤单药治疗以及甲氨蝶呤与传统和生物改善病情抗风湿药物联合治疗类风湿关节炎:一项网状荟萃分析。
Cochrane Database Syst Rev. 2016 Aug 29;2016(8):CD010227. doi: 10.1002/14651858.CD010227.pub2.
7
Hepatic Sarcoidosis.肝结节病。
J Clin Transl Hepatol. 2013 Dec;1(2):87-93. doi: 10.14218/JCTH.2013.00016. Epub 2013 Dec 15.
8
Rheumatoid Nodules.类风湿结节
Dermatol Clin. 2015 Jul;33(3):361-71. doi: 10.1016/j.det.2015.03.004.
9
Hepatic Granulomas: A Review With Emphasis on Infectious Causes.肝肉芽肿:以感染性病因为主的综述
Arch Pathol Lab Med. 2015 Jul;139(7):867-75. doi: 10.5858/arpa.2014-0123-RA.
10
Incidence of extraarticular rheumatoid arthritis in Olmsted County, Minnesota, in 1995-2007 versus 1985-1994: a population-based study.1995-2007 年与 1985-1994 年明尼苏达州奥姆斯特德县类风湿关节炎关节外发病率:一项基于人群的研究。
J Rheumatol. 2011 Jun;38(6):983-9. doi: 10.3899/jrheum.101133. Epub 2011 Apr 1.